S100 proteins as novel therapeutic targets in psoriasis and other autoimmune diseases

K Kurpet, G Chwatko - Molecules, 2022 - mdpi.com
Psoriasis is one of the most common inflammatory skin diseases affecting about 1–3% of the
population. One of the characteristic abnormalities in psoriasis is the excessive production of …

[HTML][HTML] S100 proteins: Diagnostic and prognostic biomarkers in laboratory medicine

CW Heizmann - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
S100 proteins are members of the superfamily of Ca 2+-binding proteins characterized by
the specific Ca 2+-binding motif, the EF-hand. Proteins of this superfamily are of clinical use …

Identification of an eight-gene signature for survival prediction for patients with hepatocellular carcinoma based on integrated bioinformatics analysis

G Qiao, L Chen, J Wu, Z Li - PeerJ, 2019 - peerj.com
Background Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-
related death worldwide. Despite recent advances in imaging techniques and therapeutic …

[HTML][HTML] Identification of the prognostic value of immune gene signature and infiltrating immune cells for esophageal cancer patients

L Wang, Q Wei, M Zhang, L Chen, Z Li, C Zhou… - International …, 2020 - Elsevier
Background Esophageal cancer (ESCA) is one of the deadliest solid malignancies with
worse survival rate worldwide. Here, we aimed to establish an immune-gene prognostic …

Ca2+-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets

CW Heizmann - Calcium-binding proteins of the EF-hand superfamily …, 2019 - Springer
A multitude of Ca 2+-sensor proteins containing the specific Ca 2+-binding motif (helix-loop-
helix, called EF-hand) are of major clinical relevance in a many human diseases …

Transcriptomics of canine inflammatory mammary cancer treated with empty cowpea mosaic virus implicates neutrophils in anti-tumor immunity

L Barreno, N Sevane, G Valdivia… - International Journal of …, 2023 - mdpi.com
Canine inflammatory mammary cancer (IMC) is a highly aggressive and lethal cancer in
dogs serving as a valuable animal model for its human counterpart, inflammatory breast …

Blocking the interaction between S100A9 and RAGE V domain using CHAPS molecule: A novel route to drug development against cell proliferation

CC Chang, I Khan, KL Tsai, H Li, LW Yang… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Abstract Human S100A9 (Calgranulin B) is a Ca 2+-binding protein, from the S100 family,
that often presents as a homodimer in myeloid cells. It becomes an important mediator …

Isolation and Characterization of Serum Extracellular Vesicles (EVs) from Atlantic Salmon Infected with Piscirickettsia Salmonis

L Lagos, J Tandberg, A Kashulin-Bekkelund… - Proteomes, 2017 - mdpi.com
Secretion of extracellular vesicles (EVs) is a common feature of both eukaryotic and
prokaryotic cells. Isolated EVs have been shown to contain different types of molecules …

Serum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival

P Karihtala, SK Leivonen, U Puistola… - Breast Cancer …, 2024 - Springer
Background Breast cancers exhibit considerable heterogeneity in their biology, immunology,
and prognosis. Currently, no validated, serum protein-based tools are available to evaluate …

The role of surgical tissue injury and intraoperative sympathetic activation in postoperative immunosuppression after breast-conserving surgery versus mastectomy: a …

LMC Jacobs, LS Helder, KI Albers, J Kranendonk… - Breast Cancer …, 2024 - Springer
Background Breast cancer is the second most common cause of death from cancer in
women worldwide. Counterintuitively, large population-based retrospective trials report …