Microtechnology-based methods for organoid models
V Velasco, SA Shariati, R Esfandyarpour - Microsystems & …, 2020 - nature.com
Innovations in biomaterials and stem cell technology have allowed for the emergence of
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …
Focal adhesion dynamics in cellular function and disease
YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification
To establish and maintain organ structure and function, tissues need to balance stem cell
proliferation and differentiation rates and coordinate cell fate with position. By quantifying …
proliferation and differentiation rates and coordinate cell fate with position. By quantifying …
Spatial organization of the extracellular matrix regulates cell–cell junction positioning
Q Tseng, E Duchemin-Pelletier… - Proceedings of the …, 2012 - National Acad Sciences
The organization of cells into epithelium depends on cell interaction with both the
extracellular matrix (ECM) and adjacent cells. The role of cell–cell adhesion in the regulation …
extracellular matrix (ECM) and adjacent cells. The role of cell–cell adhesion in the regulation …
Oncogene-like induction of cellular invasion from centrosome amplification
Centrosome amplification has long been recognized as a feature of human tumours;
however, its role in tumorigenesis remains unclear. Centrosome amplification is poorly …
however, its role in tumorigenesis remains unclear. Centrosome amplification is poorly …
Micropatterning as a tool to decipher cell morphogenesis and functions
M Théry - Journal of cell science, 2010 - journals.biologists.com
In situ, cells are highly sensitive to geometrical and mechanical constraints from their
microenvironment. These parameters are, however, uncontrolled under classic culture …
microenvironment. These parameters are, however, uncontrolled under classic culture …
External forces control mitotic spindle positioning
The response of cells to forces is essential for tissue morphogenesis and homeostasis. This
response has been extensively investigated in interphase cells, but it remains unclear how …
response has been extensively investigated in interphase cells, but it remains unclear how …
β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments
How different integrins that bind to the same type of extracellular matrix protein mediate
specific functions is unclear. We report the functional analysis of β1-and αv-class integrins …
specific functions is unclear. We report the functional analysis of β1-and αv-class integrins …
Stress fibres are embedded in a contractile cortical network
Contractile actomyosin networks are responsible for the production of intracellular forces.
There is increasing evidence that bundles of actin filaments form interconnected and …
There is increasing evidence that bundles of actin filaments form interconnected and …
ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1
R Sannerud, I Declerck, A Peric… - Proceedings of the …, 2011 - National Acad Sciences
Amyloid β (Aβ) peptides, the primary constituents of senile plaques and a hallmark in
Alzheimer's disease pathology, are generated through the sequential cleavage of amyloid …
Alzheimer's disease pathology, are generated through the sequential cleavage of amyloid …