Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it
accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike …

Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …

In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

The prevalence of obesity-related glomerulopathy is increasing in parallel with the
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …

Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …

Fatty acid and fat synthesis in the liver is a highly regulated metabolic pathway that is
important for very low-density lipoprotein (VLDL) production and thus energy distribution to …

Dyslipidaemia is a hallmark of chronic kidney disease (CKD). The severity of dyslipidaemia
not only correlates with CKD stage but is also associated with CKD-associated …

Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but
detectable expression of adiponectin can be observed in cell types beyond adipocytes …

There is very limited human renal sodium gradient-dependent glucose transporter protein
(SGLT2) mRNA and protein expression data reported in the literature. The first aim of this …

In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …