Achalasia

E Savarino, S Bhatia, S Roman, D Sifrim… - Nature Reviews …, 2022 - nature.com
Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired
relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in …

Efficacy of surgical or endoscopic treatment of idiopathic achalasia: a systematic review and network meta-analysis

P Mundre, CJ Black, N Mohammed… - The lancet …, 2021 - thelancet.com
Background Treatment of achalasia has changed substantially over the past 20 years.
Therapeutic options offered to patients vary, depending on access to both resources and …

The 2018 ISDE achalasia guidelines

G Zaninotto, C Bennett, G Boeckxstaens… - Diseases of the …, 2018 - academic.oup.com
Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence
of relaxations of the lower esophageal sphincter and of peristalsis along the esophageal …

ACG clinical guidelines: clinical use of esophageal physiologic testing

CP Gyawali, DA Carlson, JW Chen… - Official journal of the …, 2020 - journals.lww.com
Esophageal symptoms are common and may indicate the presence of gastroesophageal
reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or …

ASGE guideline on the management of achalasia

MA Khashab, MF Vela, N Thosani, D Agrawal… - Gastrointestinal …, 2020 - Elsevier
Achalasia is a primary esophageal motor disorder of unknown etiology characterized by
degeneration of the myenteric plexus, which results in impaired relaxation of the …

ACG clinical guidelines: diagnosis and management of achalasia

MF Vaezi, JE Pandolfino, RH Yadlapati… - Official journal of the …, 2020 - journals.lww.com
Achalasia is an esophageal motility disorder characterized by aberrant peristalsis and
insufficient relaxation of the lower esophageal sphincter. Patients most commonly present …

Peroral endoscopic myotomy: anterior versus posterior approach: a randomized single-blinded clinical trial

MA Khashab, O Sanaei, J Rivory, N Eleftheriadis… - Gastrointestinal …, 2020 - Elsevier
Background and Aims Peroral endoscopic myotomy (POEM) has become the mainstay for
the treatment of achalasia at many institutions around the world since its inception in 2008 …

Upper gastrointestinal functional and motility disorders in children

J Miller, J Khlevner, L Rodriguez - Pediatric Clinics, 2021 - pediatric.theclinics.com
The upper esophageal sphincter (UES), consisting of the cricopharyngeus muscle among
others, remains tonically contracted to prevent air entry into the esophagus or reflux of …

From Chicago classification v3. 0 to v4. 0: Diagnostic changes and clinical implications

M Sallette, J Lenz, F Mion… - Neurogastroenterology & …, 2023 - Wiley Online Library
Abstract Background The Chicago Classification (CC) used to define esophageal motility
disorders in high‐resolution manometry (HRM) has evolved over time. Our aim was to …

Functional lumen imaging probe panometry helps identify clinically relevant esophagogastric junction outflow obstruction per Chicago classification v4. 0

DA Carlson, JM Schauer, W Kou… - Official journal of the …, 2023 - journals.lww.com
METHODS: An observational cohort study was performed on patients who completed FLIP
during endoscopy and had an HRM/CCv4. 0 diagnosis of EGJOO, ie, HRM-EGJOO …