AhR and Wnt/β-catenin signaling pathways and their interplay
AY Grishanova, LS Klyushova… - Current Issues in …, 2023 - mdpi.com
As evolutionarily conserved signaling cascades, AhR and Wnt signaling pathways play a
critical role in the control over numerous vital embryonic and somatic processes. AhR …
critical role in the control over numerous vital embryonic and somatic processes. AhR …
Comparison of antagonistic effects of nanoparticle-selenium, selenium-enriched yeast and sodium selenite against cadmium-induced cardiotoxicity via AHR/CAR …
J Ge, K Guo, Y Huang, PD Morse, C Zhang… - The Journal of nutritional …, 2022 - Elsevier
Selenium (Se), a nutritionally essential mineral for humans and animals, has a significant
antagonistic effect on heavy metal cadmium (Cd) biotoxicity. Still, the impact of different Se …
antagonistic effect on heavy metal cadmium (Cd) biotoxicity. Still, the impact of different Se …
An integrative data-centric approach to derivation and characterization of an adverse outcome pathway network for cadmium-induced toxicity
Cadmium is a prominent toxic heavy metal that contaminates both terrestrial and aquatic
environments. Owing to its high biological half-life and low excretion rates, cadmium causes …
environments. Owing to its high biological half-life and low excretion rates, cadmium causes …
Mechanisms of Heavy Metal Cadmium (Cd)-Induced Malignancy
H Wang, X Gan, Y Tang - Biological Trace Element Research, 2024 - Springer
The environmental pollution of cadmium is worsening, and its significant carcinogenic
effects on humans have been confirmed. Cadmium can induce cancer through various …
effects on humans have been confirmed. Cadmium can induce cancer through various …
Cadmium exposure induces mitochondrial pathway apoptosis in swine myocardium through xenobiotic receptors-mediated CYP450s activation
X Zhao, X Li, S Wang, Z Yang, H Liu, S Xu - Journal of Inorganic …, 2021 - Elsevier
Cadmium (Cd) pollution has become an important public and environmental health issue.
Xenobiotic receptors (XRs, aryl hydrocarbon receptor, AHR; constitutive androstane …
Xenobiotic receptors (XRs, aryl hydrocarbon receptor, AHR; constitutive androstane …
An endogenous ligand of aryl hydrocarbon receptor 6-formylindolo [3, 2-b] carbazole (FICZ) is a signaling molecule in neurogenesis of adult hippocampal neurons
M Keshavarzi, MJ Khoshnoud… - Journal of Molecular …, 2020 - Springer
Neurogenesis is a dynamic and physiologic developmental process that affects learning and
hippocampal dependent memory. It is regulated by multi-cellular micro-environment and …
hippocampal dependent memory. It is regulated by multi-cellular micro-environment and …
Anti-androgenic effect of 6-formylindolo [3, 2-b] carbazole (FICZ) in LNCaP cells is mediated by the aryl hydrocarbon-androgen receptors cross-talk
MR Arabnezhad, N Montazeri-Najafabady… - Steroids, 2020 - Elsevier
The factual impact of endogenously activated AHR by 6-formylindolo [3, 2-b] carbazole
(FICZ), an endogenous ligand of AHR on androgen receptor (AR) was aim of this study. In …
(FICZ), an endogenous ligand of AHR on androgen receptor (AR) was aim of this study. In …
The interplay of aryl hydrocarbon receptor/WNT/CTNNB1/Notch signaling pathways regulate amyloid beta precursor mRNA/protein expression and effected the …
M Keshavarzi, F Moradbeygi, K Mobini… - Toxicology …, 2022 - academic.oup.com
The amyloid beta precursor protein (APP) plays a pathophysiological role in the
development of Alzheimer's disease as well as a physiological role in neuronal growth and …
development of Alzheimer's disease as well as a physiological role in neuronal growth and …
Aryl hydrocarbon receptor is involved in the proinflammatory cytokine response to cadmium
J Kulas, D Tucovic, M Zeljkovic, D Popovic… - Biomedical and …, 2021 - Elsevier
Objective To investigate involvement of the aryl hydrocarbon receptor (AhR) in the
immunomodulatory effects of cadmium (Cd). Methods The effect of Cd on AhR activation …
immunomodulatory effects of cadmium (Cd). Methods The effect of Cd on AhR activation …
2, 2′, 4, 4′‐Tetrabromodiphenyl ether and cadmium co‐exposure activates aryl hydrocarbon receptor pathway to induce ROS and GSDME‐dependent pyroptosis in …
Y Sheng, C Zhang, D Cai, G Xu, S Chen… - Environmental …, 2024 - Wiley Online Library
We have previously found that a mixture exposure of 2, 2′, 4, 4′‐tetrabromodiphenyl ether
(BDE‐47) and cadmium (Cd) causes kidney damage; however, the mechanism was not fully …
(BDE‐47) and cadmium (Cd) causes kidney damage; however, the mechanism was not fully …