Antibiotic therapy through short-term or repeated long-term prescriptions can have several
damaging effects on the normal microbiota of the gastrointestinal tract. Changes in …

Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Following the new ESPEN Standard Operating Procedures, the previous guidelines to
provide best medical nutritional therapy to critically ill patients have been updated. These …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary …

Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …

The composition of the lung microbiome is increasingly well characterised, with changes in
microbial diversity or abundance observed in association with several chronic respiratory …

Background Exacerbations of asthma cause a substantial global illness burden. Adults with
uncontrolled persistent asthma despite maintenance treatment require additional therapy …

Bronchiectasis is characterised by pathological dilation of the airways. More specifically, the
radiographic demonstration of airway enlargement is the common feature of a …

Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are
no established therapies that directly target neutrophilic inflammation because little is …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …