Medicinal importance and chemosensing applications of pyridine derivatives: a review

G Mohammad Abu-Taweel, MM Ibrahim… - Critical Reviews in …, 2024 - Taylor & Francis
Pyridine derivatives are the most common and significant heterocyclic compounds, which
play an important role in various fields ranging from medicinal to chemosensing …

Antimicrobial, antioxidant, cell imaging and sensing applications of fluorescein derivatives: A review

AH Alharbi, S Khan - Analytical Biochemistry, 2024 - Elsevier
Fluorescein itself is a synthetic organic compound and a prominent member of the xanthene
dye family. It exhibits strong fluorescence under ultraviolet (UV) or blue light excitation …

Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties

HA Abou‐Zied, EAM Beshr, HAM Gomaa… - Archiv der …, 2023 - Wiley Online Library
As dual EGFR and BRAFV600E inhibitors, 2‐(3‐cyano‐4, 6‐bis (aryl)‐2‐oxo‐1, 2‐
dihydropyridine‐1‐yl)‐N‐(4‐cinnamoylphenyl) acetamide derivatives 8–20 were developed …

Synthesis and antitumor evaluation of some new thiazolopyridine, nicotinonitrile, pyrazolopyridine, and polyhydroquinoline derivatives using ceric ammonium nitrate …

RR Raslan, SA Hessein, SA Fouad… - Journal of …, 2022 - Wiley Online Library
A novel series of thiazolo [5, 4‐b] pyridine, polysubstituted pyridines, pyrazolo [3, 4‐b]
pyridine‐5‐carbonitriles, and polyhydroquinoline were synthesized via one‐pot reaction of 2 …

Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR …

LH Al-Wahaibi, HA Abou-Zied, M Hisham, EAM Beshr… - Molecules, 2023 - mdpi.com
A series of novel 3-cyanopyridone/pyrazoline hybrids (21–30) exhibiting dual inhibition
against EGFR and BRAFV600E has been developed. The synthesized target compounds …

Heterocycles 39. Synthesis, characterization and evaluation of the anti-inflammatory activity of thiazolo [3, 2-b][1, 2, 4] triazole derivatives bearing pyridin-3/4-yl moiety

A Toma, C Mogoşan, L Vlase, D Leonte… - Medicinal Chemistry …, 2017 - Springer
Abstract A series of pyridin-3/4-yl-thiazolo [3, 2-b][1, 2, 4] triazole derivatives (5a–g, 6a–g)
were synthesised by Hantzsch condensation of 5-pyridin-3/4-yl-1, 2, 4-triazole-3-thiol and …

The chemo-and regioselectivity of the cyclization of thiosemicarbazides with haloacetic acids and their derivatives

AN Izmest'ev, AА Streltsov, AN Kravchenko… - Chemistry of …, 2022 - Springer
The Chemo- and Regioselectivity of the Cyclization of Thiosemicarbazides with Haloacetic Acids
and their Derivatives | Chemistry of Heterocyclic Compounds Skip to main content SpringerLink …

3-Cyano-2-oxa-pyridines: a promising template for diverse pharmacological activities

AK Bass, E Abdelhafez, M El-Zoghbi… - Journal of advanced …, 2021 - journals.ekb.eg
Pyridines have occupied a unique place in medicinal chemistry as it is widely profound as
natural products and formed the integral backbone of great number of drugs in the market. In …

Bis (pyridine) enaminone as a Precursor for the Synthesis of Bis (azoles) and Bis (azine) Utilizing Recent Economic Green Chemistry Technology: The Q-Tube System

KM Al-Zaydi, TS Saleh, NF Alqahtani, MS Bagazi - Molecules, 2023 - mdpi.com
We reported herein efficient economic high-pressure synthesis procedures for the synthesis
of bis (azoles) and bis (azines) by utilizing the bis (enaminone) intermediate. Bis …

[HTML][HTML] Synthesis, characterization and toxicity studies of pyridinecarboxaldehydes and L-tryptophan derived Schiff bases and corresponding copper (II) complexes

M Malakyan, N Babayan, R Grigoryan… - …, 2016 - ncbi.nlm.nih.gov
Schiff bases and their metal-complexes are versatile compounds exhibiting a broad range of
biological activities and thus actively used in the drug development process. The aim of the …