Single nucleotide polymorphisms (SNPs) are an abundant form of genome variation,
distinguished from rare variations by a requirement for the least abundant allele to have a …

Genetic mapping provides a powerful approach to identify genes and biological processes
underlying any trait influenced by inheritance, including human diseases. We discuss the …

Advances in next generation technologies have driven the costs of DNA sequencing down
to the point that genotyping-by-sequencing (GBS) is now feasible for high diversity, large …

The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in …

We describe a map of 1.42 million single nucleotide polymorphisms (SNPs) distributed
throughout the human genome, providing an average density on available sequence of one …

SNP genotyping arrays have been useful for many applications that require a large number
of molecular markers such as high-density genetic mapping, genome-wide association …

For a long time the study of evolution has been based on morphology; the long neck of a
giraffe, the human brain, a bird's wing, and so on. Morphological change in evolution is …

Enormous progress in mapping complex traits in humans has been made in the last 5 yr.
There has been early success for prevalent diseases with complex phenotypes. These …

Abstract 'Orang-utan'is derived from a Malay term meaning 'man of the forest'and aptly
describes the southeast Asian great apes native to Sumatra and Borneo. The orang-utan …

A fully updated guide to the increasingly prevalent use of molecular data in ecological
studies Molecular ecology is concerned with how molecular biology and population genetics …