Measurement and clinical significance of lipid peroxidation as a biomarker of oxidative stress: oxidative stress in diabetes, atherosclerosis, and chronic inflammation

F Ito, Y Sono, T Ito - Antioxidants, 2019 - mdpi.com
Endothelial dysfunction is one of the initial steps in the pathogenesis of atherosclerosis and
development of cardiovascular disease in patients with diabetes mellitus. Several risk …

Coronary artery disease: from mechanism to clinical practice

C Shao, J Wang, J Tian, Y Tang - Coronary Artery Disease: Therapeutics …, 2020 - Springer
In most developed countries, coronary artery disease (CAD), mostly caused by
atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to …

The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective

SS Mahmood, D Levy, RS Vasan, TJ Wang - The lancet, 2014 - thelancet.com
Summary On Sept 29, 2013, the Framingham Heart Study will celebrate 65 years since the
examination of the first volunteer in 1948. During this period, the study has provided …

Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Mitohormesis: promoting health and lifespan by increased levels of reactive oxygen species (ROS)

M Ristow, K Schmeisser - Dose-response, 2014 - journals.sagepub.com
Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review

AD Colosia, R Palencia, S Khan - Diabetes, metabolic syndrome …, 2013 - Taylor & Francis
Background Hypertension and obesity are known to contribute, directly or indirectly, to the
development of long-term complications of type 2 diabetes mellitus (T2DM). Knowing the …

The global burden of diabetes and its complications: an emerging pandemic

D Susan van, JWJ Beulens… - European Journal of …, 2010 - academic.oup.com
The number of patients with type 2 diabetes is increasing rapidly in both developed and
developing countries around the world. The emerging pandemic is driven by the combined …

Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial

J Stamler, O Vaccaro, JD Neaton, D Wentworth… - Diabetes …, 1993 - Am Diabetes Assoc
OBJECTIVE To assess predictors of CVD mortality among men with and without diabetes
and to assess the independent effect of diabetes on the risk of CVD death. RESEARCH …

Impact of postprandial glycaemia on health and prevention of disease

EE Blaak, JM Antoine, D Benton, I Björck… - Obesity …, 2012 - Wiley Online Library
Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been
implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes …

Confidence intervals rather than P values: estimation rather than hypothesis testing.

MJ Gardner, DG Altman - Br Med J (Clin Res Ed), 1986 - bmj.com
Overemphasis on hypothesis testing--and the use of P values to dichotomise significant or
non-significant results--has detracted from more useful approaches to interpreting study …