Nanoparticle diffusion in respiratory mucus influenced by mucociliary clearance: a review of mathematical modeling
Background: Inhalation and deposition of particles in human airways have attracted
considerable attention due to importance of particulate pollutants, transmission of infectious …
considerable attention due to importance of particulate pollutants, transmission of infectious …
Nanomedicines for intranasal delivery: understanding the nano-bio interactions at the nasal mucus-mucosal barrier
T Hua, S Li, B Han - Expert Opinion on Drug Delivery, 2024 - Taylor & Francis
Introduction Intranasal administration is an effective drug delivery routes in modern
pharmaceutics. However, unlike other in vivo biological barriers, the nasal mucosal barrier is …
pharmaceutics. However, unlike other in vivo biological barriers, the nasal mucosal barrier is …
[HTML][HTML] Three-dimensional simulation of mucociliary clearance under the ciliary abnormalities
In this study three-dimensional computational model of a segment of bronchial airway
surface liquid has been investigated to study the effect of various cilia abnormalities on …
surface liquid has been investigated to study the effect of various cilia abnormalities on …
A nonlinear viscoelastic model of mucociliary clearance
MH Sedaghat, UZ George, O Abouali - Rheologica Acta, 2021 - Springer
In this study, we implemented a two-dimensional unsteady flow model to study mucociliary
clearance. The model is defined in a two-layered geometry consisting of a Newtonian …
clearance. The model is defined in a two-layered geometry consisting of a Newtonian …
Nonlinear simulation of mucociliary clearance: a three-dimensional study
In this study three-dimensional (3D) numerical simulation of mucociliary clearance from the
lung has been studied. The major thrust of this investigation is 3D simulation of mucociliary …
lung has been studied. The major thrust of this investigation is 3D simulation of mucociliary …
The Path from Nasal Tissue to Nasal Mucosa on Chip: Part 2—Advanced Microfluidic Nasal In Vitro Model for Drug Absorption Testing
EV Koch, S Bendas, K Nehlsen, T May, S Reichl… - Pharmaceutics, 2023 - mdpi.com
The nasal mucosa, being accessible and highly vascularized, opens up new opportunities
for the systemic administration of drugs. However, there are several protective functions like …
for the systemic administration of drugs. However, there are several protective functions like …
Role of spatial heterogeneity in the collective dynamics of cilia beating in a minimal one-dimensional model
Cilia are elastic hairlike protuberances of the cell membrane found in various unicellular
organisms and in several tissues of most living organisms. In some tissues such as the …
organisms and in several tissues of most living organisms. In some tissues such as the …