Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

Simple Summary Extracellular vesicles (EVs) are membrane-bound vesicles released by all
cell types, differing in biogenesis, physical characteristics, and contents. Due to their central …

Exosomes are small extracellular vesicles released by almost all cell types in physiological
and pathological conditions. The exosomal potential to unravel disease mechanisms, or to …

Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …

Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Head and neck cancer (HNC) remains to be a major cause of mortality worldwide because
of confounding factors such as late-stage tumor diagnosis, loco-regional aggressiveness …

Intercellular communication is a normal feature of most physiological interactions between
cells in healthy organisms. While cells communicate directly through intimate physiology …

Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

Exosomes (EXOs) were given attention as an extracellular vesicle (EV) with a pivotal
pathophysiological role in the development of certain neurodegenerative disorders (NDD) …

Exosomes are small membrane vesicles (ranging from 30 nm to 150 nm), secreted by
different cell types upon fusion of multivesicular bodies (MVB) to the cell plasma membrane …