Systematic review: the role of the gut microbiota in chemotherapy‐or radiation‐induced gastrointestinal mucositis–current evidence and potential clinical applications
Y Touchefeu, E Montassier, K Nieman… - Alimentary …, 2014 - Wiley Online Library
Background Gastrointestinal mucositis is defined as inflammation and/or ulcers of the
gastrointestinal tract occurring as a complication of chemotherapy and radiation therapy …
gastrointestinal tract occurring as a complication of chemotherapy and radiation therapy …
Chemotherapy-induced constipation and diarrhea: pathophysiology, current and emerging treatments
Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked
clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and …
clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and …
The Synergistic Effects of Polysaccharides and Ginsenosides From American Ginseng (Panax quinquefolius L.) Ameliorating Cyclophosphamide-Induced Intestinal …
R Zhou, D He, J Xie, Q Zhou, H Zeng, H Li… - Frontiers in …, 2021 - frontiersin.org
Cyclophosphamide (CTX), used in cancer chemotherapy, a high dose of which would cause
immunosuppressive effect and intestinal mucosa damage. American ginseng (Panax …
immunosuppressive effect and intestinal mucosa damage. American ginseng (Panax …
Chemotherapy‐driven dysbiosis in the intestinal microbiome
E Montassier, T Gastinne, P Vangay… - Alimentary …, 2015 - Wiley Online Library
Background Chemotherapy is commonly used as myeloablative conditioning treatment to
prepare patients for haematopoietic stem cell transplantation (HSCT). Chemotherapy leads …
prepare patients for haematopoietic stem cell transplantation (HSCT). Chemotherapy leads …
[HTML][HTML] GDF15 induces anorexia through nausea and emesis
Summary Growth differentiation factor 15 (GDF15) is a cytokine that reduces food intake
through activation of hindbrain GFRAL-RET receptors and has become a keen target of …
through activation of hindbrain GFRAL-RET receptors and has become a keen target of …
Perspectives on cancer therapy‐induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients
BACKGROUND A frequent complication of anticancer treatment, oral and gastrointestinal
(GI) mucositis, threatens the effectiveness of therapy because it leads to dose reductions …
(GI) mucositis, threatens the effectiveness of therapy because it leads to dose reductions …
Clinical practice guidelines for the prevention and treatment of cancer therapy–induced oral and gastrointestinal mucositis
EB Rubenstein, DE Peterson… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Oral and gastrointestinal (GI) mucositis can affect up to 100% of patients
undergoing high‐dose chemotherapy and hematopoietic stem cell transplantation, 80% of …
undergoing high‐dose chemotherapy and hematopoietic stem cell transplantation, 80% of …
Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management
A Stein, W Voigt, K Jordan - Therapeutic advances in …, 2010 - journals.sagepub.com
Diarrhea is one of the main drawbacks for cancer patients. Possible etiologies could be
radiotherapy, chemotherapeutic agents, decreased physical performance, graft versus host …
radiotherapy, chemotherapeutic agents, decreased physical performance, graft versus host …
Emerging evidence on the pathobiology of mucositis
Background Considerable progress has been made in our understanding of the biological
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …
Manipulations of the gut microbiome alter chemotherapy-induced inflammation and behavioral side effects in female mice
Chemotherapy treatment is associated with acute behavioral side effects (fatigue, anorexia)
that significantly reduce patient quality of life and are dose-limiting, thereby increasing …
that significantly reduce patient quality of life and are dose-limiting, thereby increasing …