The accumulation of harmful substances has long been recognized as a likely cause of
many neurodegenerative diseases. The two classic brain clearance pathways are …

Precise imaging is essential for the accurate diagnosis and surgical guidance of brain
diseases but it is challenging due to the difficulties in crossing the blood-brain barrier (BBB) …

Multi-phase dynamic contrast-enhanced magnetic resonance imaging image registration
makes a substantial contribution to medical image analysis. However, existing methods (eg …

Considerable strides in medical interventions during the acute phase of traumatic brain
injury (TBI) have brought improved overall survival rates. However, following TBI, people …

The intricate relationship between the central nervous system (CNS) and the immune
system plays a crucial role in the pathogenesis of various neurological diseases …

A diverse range of genetic risk factors have been identified for diseases across the
frontotemporal dementia (FTD)–amyotrophic lateral sclerosis (ALS) spectrum, but the …

Introduction Traumatic brain injury (TBI) is one of the main reasons for disability and death in
patients. There is evidence showing exogenous nerve growth factor (NGF) can promote …

Malignant brain tumors remain deadly with a 36% five-year survival rate and 5% for
glioblastoma (GBM), the most aggressive and prevalent form of malignant brain tumor. The …