Serum uric acid is commonly elevated in subjects with chronic kidney disease (CKD), but
was historically viewed as an issue of limited interest. Recently, uric acid has been …

Daniel I. Feig1, Magdalena Madero2, Diana I. Jalal3, L. Gabriela Sanchez-Lozada4, and
Richard J. Johnson3 The 20th century witnessed an explosive increase in the frequency of …

Uric acid (UA) is the final end product of purine catabolism and is formed from xanthines and
hypoxanthines. Hyperuricemia can be secondary to either an exaggerated production of UA …

Previous studies have shown that birth weight and other birth characteristics may be
associated with risk for type 2 diabetes and cardiovascular disease (CVD) later in life; …

Elevations in serum uric acid levels in childhood are often associated with other diseases
and allied conditions. Hyperuricemia in young individuals is often a marker of the metabolic …

Primary hypertension is increasingly common and is associated with significant morbidity.
Here, we review the history of its discovery and rise during the last century with an emphasis …

Background: Persistent organic pollutants (POPs) are endocrine disruptors and have been
suggested as possible risk factors for diabetes. Few studies have been performed to …

BACKGROUND Recent studies suggest that high levels of serum uric acid of very early life
are a result of the in-utero environment and may lead to elevated blood pressure (BP) in …

With the introduction of life-course epidemiology, researchers realized the importance of
identifying risk factors in early life to prevent chronic diseases. This led to the establishment …

Objective To compare serum uric acid levels in adolescents born prematurely and
adolescents born at term and to assess the correlation between serum uric acid and blood …