Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Antimicrobial peptides, which have been isolated from many bacteria, fungi, plants,
invertebrates and vertebrates, are an important component of the natural defenses of most …

The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Antimicrobial peptides are a vital component of the innate immune system of all eukaryotic
organisms and many of these peptides have potent antifungal activity. They have potential …

The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

All living cells have an absolute requirement for K+, which must be taken up from the
external medium. In contrast to marine organisms, which live in a medium with an …

Antimicrobial peptides are ancient components of the innate immune system and have been
isolated from organisms spanning the phylogenetic spectrum. Over an evolutionary time …

Abstract Bacterial Trk and Ktr, fungal Trk and plant HKT form a family of membrane
transporters permeable to K+ and/or Na+ and characterized by a common structure probably …

Histatins are salivary cationic peptides that provide the first line of defense against oral
candidiasis caused by Candida albicans. This minireview presents a critical evaluation of …

Acquired drug resistance to mycotic infections is rapidly emerging as a major medical
problem. Opportunistic fungal infections create therapeutic challenges, particularly in high …