β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various
heterocyclic compounds. In the past decade, a number of successful reactions based on …

The effective and high yielding synthesis of poly-functionalized pyrimidines, using
multicomponent reactions (MCRs), is imperative in organic and medicinal chemistry. The …

New Biginelli adducts were rationalised, via the introduction of selected anti-tubercular (TB)
pharmacophores into the dihydropyrimidine (DHPM) ring of deoxythymidine …

Herein, we present biological studies on 3, 4-dihydropyrimidin-2 (1H)-ones (DHPMs)
obtained via Biginelli reaction catalyzed by NH4Cl under solvent-free conditions. Until now …

5-Aryl-2-furaldehydes, obtained by furfural arylation with arenediazonium salts, react with
ethyl acetoacetate or acetylacetone and (thio)-urea in the presence of FeCl 3· 6H 2 O as a …

A brief review of the publications over the past 5 years devoted to the synthesis of 3, 4-
dihydropyrimidin-2 (1 H)-one or-thione derivatives using Biginelli reaction is presented. The …

Spectroscopic studies of cyclohexenyl carbothioamides 2, obtained from condensation of 1,
3-cyclohexandione with aryl isothiocyanates, predicted the proton transfer behaviour in …

Tetrahydropyrimidine (THPM) synthesis has an enormous importance in organic chemistry
and especially in pharmaceutical applications. Pyrimidines are the most active class of N …

Indenocarbothioamides 2, obtained from reaction of indane-1, 3-dione with aryl
isothiocyanates, on condensation with 3-chloropentane-2, 4-dione and chloroacetyl chloride …

Found in natural products, and frequently used as flavoring agents or as building blocks for
pharmaceuticals, diazines and their benzo derivatives possess a diverse set of properties …