Replication of hepatitis C virus

D Moradpour, F Penin, CM Rice - Nature reviews microbiology, 2007 - nature.com
Exciting progress has recently been made in understanding the replication of hepatitis C
virus, a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma …

Assembly of infectious hepatitis C virus particles

R Bartenschlager, F Penin, V Lohmann, P André - Trends in microbiology, 2011 - cell.com
A hallmark of the hepatitis C virus (HCV) replication cycle is its tight link with host cell lipid
synthesis. This is best illustrated by the peculiar pathway used for the assembly of infectious …

Dengue virus-induced autophagy regulates lipid metabolism

NS Heaton, G Randall - Cell host & microbe, 2010 - cell.com
Autophagy influences numerous cellular processes, including innate and adaptive immunity
against intracellular pathogens. However, some viruses, including dengue virus (DENV) …

microRNA‐122 stimulates translation of hepatitis C virus RNA

JI Henke, D Goergen, J Zheng, Y Song… - The EMBO …, 2008 - embopress.org
Hepatitis C virus (HCV) is a positive strand RNA virus that propagates primarily in the liver.
We show here that the liver‐specific microRNA‐122 (miR‐122), a member of a class of small …

Regulation of hepatic innate immunity by hepatitis C virus

SM Horner, M Gale Jr - Nature medicine, 2013 - nature.com
Hepatitis C virus (HCV) is a global public health problem involving chronic infection of the
liver, which can cause liver disease and is linked with liver cancer. Viral innate immune …

Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome

A Merz, G Long, MS Hiet, B Brügger, P Chlanda… - Journal of Biological …, 2011 - ASBMB
A hallmark of hepatitis C virus (HCV) particles is their association with host cell lipids, most
notably lipoprotein components. It is thought that this property accounts for the low density of …

Role of lipids in virus replication

M Lorizate, HG Kräusslich - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Viruses intricately interact with and modulate cellular membranes at several stages of their
replication, but much less is known about the role of viral lipids compared to proteins and …

Hepatitis C virus hijacks host lipid metabolism

GH Syed, Y Amako, A Siddiqui - Trends in Endocrinology & Metabolism, 2010 - cell.com
Hepatitis C virus (HCV) enhances its replication by modulating host cell lipid metabolism.
HCV circulates in the blood in association with lipoproteins. HCV infection is associated with …

Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion

P Gastaminza, G Cheng, S Wieland, J Zhong… - Journal of …, 2008 - Am Soc Microbiol
Intracellular infectious hepatitis C virus (HCV) particles display a distinctly higher buoyant
density than do secreted virus particles, suggesting that the characteristic low density of …

Human apolipoprotein e is required for infectivity and production of hepatitis C virus in cell culture

KS Chang, J Jiang, Z Cai, G Luo - Journal of virology, 2007 - Am Soc Microbiol
Recent advances in reverse genetics of hepatitis C virus (HCV) made it possible to
determine the properties and biochemical compositions of HCV virions. Sedimentation …