The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …

Important protective roles of intestinal alkaline phosphatase (IAP)–including regulation of
intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial …

Over the past few years, the role of intestinal alkaline phosphatase (IAP) as a crucial
mucosal defence factor essential for maintaining gut homeostasis has been established. IAP …

Over the past few years, there is increasing evidence implicating a novel role for Intestinal
Alkaline Phosphatase (IAP) in mitigating inflammatory mediated disorders. IAP is an …

Intestinal alkaline phosphatase (IAP) plays an essential role in intestinal homeostasis and
health through interactions with the resident microbiota, diet and the gut. IAP's role in the …

A key aspect of postnatal intestinal adaptation is the establishment of symbiotic relationships
with co-evolved gut microbiota. Necrotizing enterocolitis (NEC) is the most severe disease …

Acute kidney injury (AKI) is a common disease in the intensive care unit and accounts for
high morbidity and mortality. Sepsis, the predominant cause of AKI in this setting, involves a …

Intestinal alkaline phosphatase (IAP) regulates bicarbonate secretion, detoxifies
lipopolysaccharide (LPS), regulates gut microbes, and dephosphorylates proinflammatory …

Inflammatory bowel disease (IBD) is more common in adults than in children. Onset of IBD
before 17 years of age is referred as pediatric onset IBD and is further categorized as very …

Side effects of proton pump inhibitors (PPI) can be linked to the changes in the intestinal
microbiome that occur during therapy, especially in long-term users. Therefore, the …