Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Despite the significant public health issue that it poses, only five medical treatments have
been approved for Alzheimer's disease (AD) and these act to control symptoms rather than …

Importance The effect of intensive blood pressure lowering on brain health remains
uncertain. Objective To evaluate the association of intensive blood pressure treatment with …

Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders
with different pathological backgrounds. The advanced vasculature net of cerebral vessels …

Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

A 'frontal variant of Alzheimer's disease'has been described in patients with predominant
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …

Vascular dementia (VaD) is recognised as a neurocognitive disorder, which is explained by
numerous vascular causes in the general absence of other pathologies. The heterogeneity …

Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid
(PUFA) found in the brain and can affect neurological function by modulating signal …