Erectile dysfunction (ED) is a disorder that often occurs in men worldwide. One of the drugs
used as the first-line therapy for erectile dysfunction is sildenafil citrate (SC). Unfortunately …

As the number of new drug candidates that are poorly soluble in water grows, new
technologies that enable the enhancement of their solubility are needed. This is the case …

Pulmonary hypertension (PH) is a cardiovascular disease affecting patient's life. Sildenafil
citrate (SC), the first-line treatment, is present in oral and injectable forms with some …

The objective of this study was to synthesize silver nanoparticles from the leaves of Tridax
procumbens and develop its topical gels using chitosan to investigate the wound healing …

Erectile dysfunction (ED) is a growing health condition that needs safe and effective therapy.
One of the main common treatments is sildenafil which is used in clinics for managing …

Olaparib (OLA) is an anticancer agent that acts by inhibiting the poly (ADP-ribose)-
polymerase-I (PARP-I). Due to its low solubility and low permeability, it has been placed as a …

Oleanolic acid (OA) is a pentacyclic triterpenoid widely found in the Oleaceae family, and it
represents 3.5% of the dry weight of olive leaves. OA has many pharmacological activities …

Abstract Red fruit (Pandanus conoideus Lam.) boasts high β-carotene (BC) content, often
consumed orally. However, absorption issues and low bioavailability due to food matrix …

The oral bioavailability of sildenafil citrate is approximately 43%, primarily limited by the low
aqueous solubility and first-pass effect. Considering the drug properties and …

This study aims to develop chitosan‐based apigenin (AGN) spray‐dried solid dispersions
(SDSDs) within a 3D pill. AGN SDSDs were prepared using 1: 1 (AC1), 1: 1.5 (AC2), and 1 …