Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Developing transmission-blocking strategies for malaria control

RE Sinden - PLoS pathogens, 2017 - journals.plos.org
Background Analysis of the varied developmental pathways exploited by malarial parasites
as they pass through their differing life stages can be challenging [1–3], the parasites often …

Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target

M Georgiades, A Alampounti, J Somers, MP Su… - Nature …, 2023 - nature.com
Malaria mosquitoes acoustically detect their mating partners within large swarms that form
transiently at dusk. Indeed, male malaria mosquitoes preferably respond to female flight …

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission

DG Paton, LM Childs, MA Itoe, IE Holmdahl… - Nature, 2019 - nature.com
Bites of Anopheles mosquitoes transmit Plasmodium falciparum parasites that cause
malaria, which kills hundreds of thousands of people every year. Since the turn of this …

A deltamethrin crystal polymorph for more effective malaria control

J Yang, B Erriah, CT Hu, E Reiter… - Proceedings of the …, 2020 - National Acad Sciences
Pyrethroid contact insecticides are mainstays of malaria control, but their efficacies are
declining due to widespread insecticide resistance in Anopheles mosquito populations, a …

Spatial distribution and habitat characterization of mosquito species during the dry season along the Mara River and its tributaries, in Kenya and Tanzania

GO Dida, DN Anyona, PO Abuom, D Akoko… - Infectious diseases of …, 2018 - Springer
Background Vector-borne diseases are increasingly becoming a major health problem
among communities living along the major rivers of Africa. Although larger water bodies …

The male mosquito contribution towards malaria transmission: Mating influences the Anopheles female midgut transcriptome and increases female susceptibility to …

FA Dahalan, TS Churcher, N Windbichler… - PLoS …, 2019 - journals.plos.org
Mating causes dramatic changes in female physiology, behaviour, and immunity in many
insects, inducing oogenesis, oviposition, and refractoriness to further mating. Females from …

20-Hydroxyecdysone primes innate immune responses that limit bacterial and malarial parasite survival in Anopheles gambiae

RA Reynolds, H Kwon, RC Smith - Msphere, 2020 - Am Soc Microbiol
Blood feeding is an integral behavior of mosquitoes to acquire nutritional resources needed
for reproduction. This requirement also enables mosquitoes to serve as efficient vectors to …

Putting evolution in elimination: winning our ongoing battle with evolving malaria mosquitoes and parasites

S Huijben, KP Paaijmans - Evolutionary applications, 2018 - Wiley Online Library
Since 2000, the world has made significant progress in reducing malaria morbidity and
mortality, and several countries in Africa, South America and South‐East Asia are working …

Steroid hormone regulation of innate immunity in Drosophila melanogaster

SA Keith - Plos Genetics, 2023 - journals.plos.org
Endocrine signaling networks control diverse biological processes and life history traits
across metazoans. In both invertebrate and vertebrate taxa, steroid hormones regulate …