Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

[HTML][HTML] Peptide-drug conjugates: a new hope for cancer management

VP Chavda, HK Solanki, M Davidson… - Molecules, 2022 - mdpi.com
Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Highly Efficient Light Helicity Detection of Enantiomers by Chiral Metal–Organic Framework Thin Films

YB Tian, K Tanaka, LM Chang, C Wöll, ZG Gu… - Nano Letters, 2023 - ACS Publications
The potential of chiral metal–organic frameworks (MOFs) for circularly polarized (CP) optics
has been largely unexplored. Herein, we have successfully deposited monolithic and highly …

Characterization of antifungal cyclic dipeptides of Lacticaseibacillus paracasei ZX1231 and active packaging film prepared with its cell-free supernatant and bacterial …

X Zheng, W Nie, J Xu, H Zhang, X Liang… - Food Research …, 2022 - Elsevier
Fungal infection and/or spoilage are major concerns of crop and food security worldwide,
prompting the developments and application of various antimicrobial agents. In this study …

Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

EM Huber - ChemBioChem, 2022 - Wiley Online Library
Epipolythiodioxopiperazines (ETPs) are fungal secondary metabolites that share a 2, 5‐
diketopiperazine scaffold built from two amino acids and bridged by a sulfide moiety …

[HTML][HTML] Structural and biofunctional insights into the Cyclo (Pro-Pro-Phe-Phe-) Scaffold from experimental and in silico studies: Melanoma and beyond

J Bojarska, M Breza, M Remko, M Czyz… - International Journal of …, 2022 - mdpi.com
Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …

Chemical synthesis in competition with global genome mining and heterologous expression for the preparation of dimeric tryptophan-derived 2, 5-dioxopiperazines

P García-Domínguez, A Areal, R Alvarez… - Natural Product …, 2022 - pubs.rsc.org
Covering: up to the end of 2021 Within the 2, 5-dioxopiperazines-containing natural
products, those generated from tryptophan allow further structural diversification due to the …

[HTML][HTML] Phytochemical Profile and Anticancer Potential of Endophytic Microorganisms from Liverwort Species, Marchantia polymorpha L.

M Stelmasiewicz, Ł Świątek, A Ludwiczuk - Molecules, 2021 - mdpi.com
Liverwort endophytes could be a source of new biologically active substances, especially
when these spore-forming plants are known to produce compounds that are not found in …

[HTML][HTML] Elucidating the mechanism of action of mycotoxins through machine learning-driven QSAR models: Focus on lipid peroxidation

M Galvez-Llompart, R Zanni, L Manyes… - Food and Chemical …, 2023 - Elsevier
Understanding the mechanisms of mycotoxin toxicity is crucial for establishing effective
guidelines and preventive strategies. In this study, machine learning models based on …

[HTML][HTML] Epiphytic and endophytic microbiome of the seagrass Zostera marina: Do they contribute to pathogen reduction in seawater?

D Tasdemir, S Scarpato, C Utermann-Thüsing… - Science of the Total …, 2024 - Elsevier
Seagrass meadows provide crucial ecosystem services for coastal environments and were
shown to reduce the abundance of waterborne pathogens linked to infections in humans …