The impact of transposable elements in adaptive evolution

L Schrader, J Schmitz - Molecular Ecology, 2019 - Wiley Online Library
The growing knowledge about the influence of transposable elements (TE s) on (a) long‐
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …

Environmentally induced plasticity of programmed DNA elimination boosts somatic variability in Paramecium tetraurelia

V Vitali, R Hagen, F Catania - Genome Research, 2019 - genome.cshlp.org
Can ecological changes impact somatic genome development? Efforts to resolve this
question could reveal a direct link between environmental changes and somatic variability …

[HTML][HTML] Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

J Talkish, H Igel, RJ Perriman, L Shiue, S Katzman… - PLoS …, 2019 - journals.plos.org
Introns are a prevalent feature of eukaryotic genomes, yet their origins and contributions to
genome function and evolution remain mysterious. In budding yeast, repression of the highly …

From intronization to intron loss: How the interplay between mRNA-associated processes can shape the architecture and the expression of eukaryotic genes

F Catania - The International Journal of Biochemistry & Cell …, 2017 - Elsevier
Transcription-coupled processes such as capping, splicing, and cleavage/polyadenylation
participate in the journey from genes to proteins. Although they are traditionally thought to …

[HTML][HTML] Intronization signatures in coding exons reveal the evolutionary fluidity of eukaryotic gene architecture

J Ryll, R Rothering, F Catania - Microorganisms, 2022 - mdpi.com
The conventionally clear distinction between exons and introns in eukaryotic genes is
actually blurred. To illustrate this point, consider sequences that are retained in mature …

[HTML][HTML] Cross-Generational Effects and Non-random Developmental Response to Temperature Variation in Paramecium

R Hagen, V Vitali, F Catania - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Unicellular organisms such as ciliates are largely neglected in research on adaptive
developmental plasticity, although their nuclear dualism offers ideal circumstances to study …

Exploring the impact of cleavage and polyadenylation factors on pre-mRNA splicing across eukaryotes

G Lepennetier, F Catania - G3: Genes, Genomes, Genetics, 2017 - academic.oup.com
In human, mouse, and Drosophila, the spliceosomal complex U1 snRNP (U1) protects
transcripts from premature cleavage and polyadenylation at proximal intronic …

Cis-acting signals modulate the efficiency of programmed DNA elimination in Paramecium tetraurelia

D Ferro, G Lepennetier, F Catania - Nucleic Acids Research, 2015 - academic.oup.com
In Paramecium, the regeneration of a functional somatic genome at each sexual event relies
on the elimination of thousands of germline DNA sequences, known as Internal Eliminated …

Enhanced plasticity of programmed DNA elimination boosts adaptive potential in suboptimal environments

V Vitali, R Hagen, F Catania - BioRxiv, 2018 - biorxiv.org
The impact of ecological changes on the development of new somatic genomes has thus far
been neglected. This oversight yields an incomplete understanding of the mechanisms that …