Zinc coordination complexes as anticancer agents
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
Antifungal activity of thiosemicarbazones, bis (thiosemicarbazones), and their metal complexes
Fungi are ubiquitous in nature, and typically cause little or no environmental or pathogenic
damage to their plant, animal, and human hosts. However, a small but growing number of …
damage to their plant, animal, and human hosts. However, a small but growing number of …
Advances in thiosemicarbazone metal complexes as anti-lung cancer agents
XG Bai, Y Zheng, J Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …
Copper complexes as antitumor agents: In vitro and in vivo evidence
Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands
LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling
Alzheimer's disease (AD) is known as one of the most devastating neurodegenerative
disease diagnosed for the old-aged people and cholinesterase inhibitors (ChEI) can be …
disease diagnosed for the old-aged people and cholinesterase inhibitors (ChEI) can be …
[HTML][HTML] Recent advances in biological and medicinal profile of schiff bases and their metal complexes: An updated version (2018–2023)
S Thakur, A Jaryal, A Bhalla - Results in Chemistry, 2024 - Elsevier
Schiff bases are most the widely used class of molecules in organic as well as in inorganic
chemistry and are well known for fabricating stable metal complexes. Schiff bases and their …
chemistry and are well known for fabricating stable metal complexes. Schiff bases and their …
Developing a novel indium (III) agent based on human serum albumin nanoparticles: integrating bioimaging and therapy
Z Zhang, T Yang, J Zhang, W Li, S Li… - Journal of Medicinal …, 2022 - ACS Publications
To effectively integrate diagnosis and therapy for tumors, we proposed to develop an indium
(In) agent based on the unique property of human serum albumin (HSA) nanoparticles …
(In) agent based on the unique property of human serum albumin (HSA) nanoparticles …
Copper (II) complexes based on thiosemicarbazone ligand: Preparation, crystal structure, Hirshfeld surface, energy framework, antiMycobacterium activity, in silico …
RAC Souza, WRP Costa, EF Faria, MAS Bessa… - Journal of Inorganic …, 2021 - Elsevier
Considering the promising previous results on the remarkable activity exhibited by cobalt (III)
and manganese (II) thiosemicarbazone compounds as antibacterial agents, the present …
and manganese (II) thiosemicarbazone compounds as antibacterial agents, the present …
Novel glycosylation zinc (II)–cryptolepine complexes perturb mitophagy pathways and trigger cancer cell apoptosis and autophagy in SK-OV-3/DDP cells
Z Zhou, LQ Du, XM Huang, LG Zhu, QC Wei… - European Journal of …, 2022 - Elsevier
With the aim of shedding some light on the mechanism of action of zinc (II) complexes in
antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc …
antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc …