Impact of Sickle Cell Disease on Affected Individuals in Nigeria: A Critical Review

OP Adigwe, G Onavbavba, SO Onoja - International Journal of …, 2023 - Taylor & Francis
Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Association of erythrocytes antioxidant enzymes and their cofactors with markers of oxidative stress in patients with sickle cell anemia

LM Al-Naama, MK Hassan, JK Mehdi - Qatar medical journal, 2015 - qscience.com
Background: Sickle cell anemia (SCA) is an inherited blood disease with known
complications as a result of certain pathophysiological dysfunctions. It has been suggested …

Influence of oxidative stress biomarkers and genetic polymorphisms on the clinical severity of hydroxyurea-free senegalese children with sickle cell anemia

F Gueye Tall, C Martin, EHM Ndour, C Faes, I Deme Ly… - Antioxidants, 2020 - mdpi.com
Oxidative stress would play a role in the pathophysiology of sickle cell anemia (SCA). We
tested the impact of common SCA genetic modifiers (alpha-thalassemia, G6PD deficiency …

Fermented goat milk improves antioxidant status and protects from oxidative damage to biomolecules during anemia recovery

J Moreno‐Fernandez, J Diaz‐Castro… - Journal of the …, 2017 - Wiley Online Library
BACKGROUND Iron deficiency anemia (IDA) is one of the most common nutritional
problems in the world, and it is accepted that reactive oxygen species (ROS) production is …

[PDF][PDF] Gastric mucosa damage and impairment of secondary immune response in dysthyroidism is associated with TNF-α expression

AF Ajayi, AA Adelakun, RE Akhigbe - Int J Biol Med Res, 2017 - researchgate.net
Aim: This study aims to determine the relationship between immune response in rats with
altered thyroid state and expression of TNF-α in gastric tissue. Methods: Thirty male wistar …

[HTML][HTML] Respiratory burst enzymes, pro-oxidants and antioxidants status in Bangladeshi population with β-thalassemia major

MF Hossain, M Ismail, AR Tanu… - North American Journal …, 2015 - ncbi.nlm.nih.gov
Background: Oxidative stress is intimately associated with many diseases, including β-
thalassemia. Aim: The study was to estimate the status of respiratory burst enzymes, pro …

Assessment of humoral immunity and nutritionally essential trace elements in steady-state sickle cell disease Nigerian children before and after Prevenar 13 …

GO Arinola, E Disu, A Babatunde, C Olopade… - Blood Science, 2022 - mednexus.org
Background: Children with sickle cell disease (SCD) are particularly prone to pneumococcal
infection and administration of Prevenar 13 pneumococcal vaccine in Nigerian children with …

[PDF][PDF] Inflammation rather than oxidative stress is a better marker for preeclampsia

IO Adediji, AA Adelakun, EN Adejumo… - Med J Obstet …, 2016 - academia.edu
Background: Preeclampsia is a leading cause of maternal morbidity and mortality,
characterised by hypertension and significant proteinuria with or without oedema occurring …

[PDF][PDF] Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell …

ID Ly, V Pialoux, P Connes, PM Gueye, RN Diallo… - academia.edu
Oxidative stress would play a role in the pathophysiology of sickle cell anemia (SCA). We
tested the impact of common SCA genetic modifiers (alpha-thalassemia, G6PD deficiency …

[PDF][PDF] The Antioxidant Status of Patients with Sickle Cell Anaemia in the Niger Delta Region of Nigeria

FC Ezeiruaku, EM Eze, DC Ukaji - researchgate.net
Sickle cell Anaemia (SCA) is an inherited blood disorder that is associated with several
complications, including oxidative stress and generation of free radicals. This class of …