Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Ten years ago next-generation sequencing (NGS) technologies appeared on the market.
During the past decade, tremendous progress has been made in terms of speed, read …

The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

Ancient DNA is typically highly degraded with appreciable cytosine deamination, and
contamination with present-day DNA often complicates the identification of endogenous …

Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

We report a high-quality draft genome sequence of the domesticated apple (Malus×
domestica). We show that a relatively recent (> 50 million years ago) genome-wide …

One enduring question in evolutionary biology is the extent of archaic admixture in the
genomes of present-day populations. In this paper, we present a test for ancient admixture …

The seminal importance of DNA sequencing to the life sciences, biotechnology and
medicine has driven the search for more scalable and lower-cost solutions. Here we …

The geographic and temporal origins of the domestic dog remain controversial, as genetic
data suggest a domestication process in East Asia beginning 15,000 years ago, whereas …

Demand has never been greater for revolutionary technologies that deliver fast, inexpensive
and accurate genome information. This challenge has catalysed the development of next …