Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
Prognostic and predictive biomarkers in gliomas
P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …
genetic research and advanced statistical methods, revolutionize the therapeutic approach …
Integrating liquid biopsies into the management of cancer
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …
compete with one another, with selective pressures leading to the emergence of …
Current challenges and opportunities in treating glioblastoma
A Shergalis, A Bankhead, U Luesakul… - Pharmacological …, 2018 - ASPET
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …
Imaging extracellular vesicles: current and emerging methods
STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
Technical challenges of working with extracellular vesicles
Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
RNA in extracellular vesicles
Cells release a range of membrane‐enclosed extracellular vesicles (EVs) into the
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …
A rigorous method to enrich for exosomes from brain tissue
Extracellular vesicles, including exosomes, are released by all cells, including those of the
nervous system. Capable of delivering lipid, protein and nucleic acids to both nearby and …
nervous system. Capable of delivering lipid, protein and nucleic acids to both nearby and …
Liquid biopsy in gliomas: A RANO review and proposals for clinical applications
R Soffietti, C Bettegowda, IK Mellinghoff… - Neuro …, 2022 - academic.oup.com
Background There is an extensive literature highlighting the utility of blood-based liquid
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …
[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …