Mitigating radiotoxicity in the central nervous system: Role of proton therapy
Opinion statement Central nervous system (CNS) radiotoxicity remains a challenge in neuro-
oncology. Dose distribution advantages of protons over photons have prompted increased …
oncology. Dose distribution advantages of protons over photons have prompted increased …
Use of a commercial 7-T MRI scanner for clinical brain imaging: indications, protocols, challenges, and solutions—a single-center experience
C Özütemiz, M White, W Elvendahl… - American Journal of …, 2023 - Am Roentgen Ray Soc
The first commercially available 7-T MRI scanner (Magnetom Terra) was approved by the
FDA in 2017 for clinical imaging of the brain and knee. After initial protocol development and …
FDA in 2017 for clinical imaging of the brain and knee. After initial protocol development and …
Neurocognitive and radiological changes after cranial radiation therapy in humans and rodents: a systematic review
WD Perez, CJ Perez-Torres - International Journal of Radiation …, 2023 - Taylor & Francis
Background Radiation-induced brain injury is a common long-term side effect for brain
cancer survivors, leading to a reduced quality of life. Although there is growing research …
cancer survivors, leading to a reduced quality of life. Although there is growing research …
SWI by 7T MR imaging for the microscopic imaging diagnosis of astrocytic and oligodendroglial tumors
M Natsumeda, H Matsuzawa… - American Journal …, 2022 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Despite advances in molecular imaging, preoperative
diagnosis of astrocytomas and oligodendrogliomas can be challenging. In the present study …
diagnosis of astrocytomas and oligodendrogliomas can be challenging. In the present study …
Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling
Whole brain irradiation (WBI) therapy is an important treatment for brain metastases and
potential microscopic malignancies. WBI promotes progressive cognitive dysfunction in over …
potential microscopic malignancies. WBI promotes progressive cognitive dysfunction in over …
Unique brain injury patterns after proton vs photon radiotherapy for WHO grade 2-3 gliomas
Background Central nervous system (CNS) injury following brain-directed radiotherapy
remains a major challenge. Proton radiotherapy (PRT) minimizes radiation to healthy brain …
remains a major challenge. Proton radiotherapy (PRT) minimizes radiation to healthy brain …
Functional network alterations in young brain tumor patients with radiotherapy-induced memory impairments and vascular injury
MA Morrison, S Walter, S Mueller, E Felton… - Frontiers in …, 2022 - frontiersin.org
Background Cognitive impairment and cerebral microbleeds (CMBs) are long-term side-
effects of cranial radiation therapy (RT). Previously we showed that memory function is …
effects of cranial radiation therapy (RT). Previously we showed that memory function is …
An integrated analysis of clinical, genomic, and imaging features reveals predictors of neurocognitive outcomes in a longitudinal cohort of pediatric cancer survivors …
C Kline, S Stoller, L Byer, D Samuel, JM Lupo… - Frontiers in …, 2022 - frontiersin.org
Background Neurocognitive deficits in pediatric cancer survivors occur frequently; however,
individual outcomes are unpredictable. We investigate clinical, genetic, and imaging …
individual outcomes are unpredictable. We investigate clinical, genetic, and imaging …
Relationship between radiation dose and cerebral microbleed formation in dogs with intracranial tumors
C Staudinger, M Dennler, M Körner… - Journal of Veterinary …, 2024 - Wiley Online Library
Abstract Background Cerebral microbleeds (CMBs) are a possible sequela in human brain
tumor patients treated with radiation therapy (RT). No such association is reported in dogs …
tumor patients treated with radiation therapy (RT). No such association is reported in dogs …
DeepSWI: Using Deep Learning to Enhance Susceptibility Contrast on T2*‐Weighted MRI
O Genc, MA Morrison… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Although susceptibility‐weighted imaging (SWI) is the gold standard for
visualizing cerebral microbleeds (CMBs) in the brain, the required phase data are not …
visualizing cerebral microbleeds (CMBs) in the brain, the required phase data are not …