The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
Susceptibility-weighted imaging: technical essentials and clinical neurologic applications
Susceptibility-weighted imaging (SWI) evolved from simple two-dimensional T2*-weighted
sequences to three-dimensional sequences with improved spatial resolution and enhanced …
sequences to three-dimensional sequences with improved spatial resolution and enhanced …
Mechanisms and clinical implications of intervertebral disc calcification
Low back pain is a leading cause of disability worldwide. Intervertebral disc (IVD)
degeneration is often associated with low back pain but is sometimes asymptomatic. IVD …
degeneration is often associated with low back pain but is sometimes asymptomatic. IVD …
Biomarkers in Alzheimer's disease: role in early and differential diagnosis and recognition of atypical variants
B Dubois, CAF von Arnim, N Burnie, S Bozeat… - Alzheimer's Research & …, 2023 - Springer
Background Development of in vivo biomarkers has shifted the diagnosis of Alzheimer's
disease (AD) from the later dementia stages of disease towards the earlier stages and has …
disease (AD) from the later dementia stages of disease towards the earlier stages and has …
Iron, myelin, and the brain: neuroimaging meets neurobiology
Although iron is crucial for neuronal functioning, many aspects of cerebral iron biology await
clarification. The ability to quantify specific iron forms in the living brain would open new …
clarification. The ability to quantify specific iron forms in the living brain would open new …
Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives
Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …
Probing myelin content of the human brain with MRI: A review
Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
STrategically Acquired Gradient Echo (STAGE) imaging, part I: Creating enhanced T1 contrast and standardized susceptibility weighted imaging and quantitative …
Purpose To provide whole brain grey matter (GM) to white matter (WM) contrast enhanced
T1W (T1WE) images, multi-echo quantitative susceptibility mapping (QSM), proton density …
T1W (T1WE) images, multi-echo quantitative susceptibility mapping (QSM), proton density …
Quantitative susceptibility mapping as an imaging biomarker for Alzheimer's disease: The expectations and limitations
Alzheimer's disease (AD) is the most common type of dementia and a distressing diagnosis
for individuals and caregivers. Researchers and clinical trials have mainly focused on β …
for individuals and caregivers. Researchers and clinical trials have mainly focused on β …
Quantifying iron content in magnetic resonance imaging
K Ghassaban, S Liu, C Jiang, EM Haacke - Neuroimage, 2019 - Elsevier
Measuring iron content has practical clinical indications in the study of diseases such as
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …