[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

[HTML][HTML] Lessons from the cancer genome

LA Garraway, ES Lander - Cell, 2013 - cell.com
Systematic studies of the cancer genome have exploded in recent years. These studies
have revealed scores of new cancer genes, including many in processes not previously …

Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma

MA Gillette, S Satpathy, S Cao, SM Dhanasekaran… - Cell, 2020 - cell.com
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …

[HTML][HTML] Defining a cancer dependency map

A Tsherniak, F Vazquez, PG Montgomery, BA Weir… - Cell, 2017 - cell.com
Most human epithelial tumors harbor numerous alterations, making it difficult to predict
which genes are required for tumor survival. To systematically identify cancer dependencies …

[HTML][HTML] Comprehensive molecular profiling of lung adenocarcinoma

Cancer Genome Atlas Research Network - Nature, 2014 - ncbi.nlm.nih.gov
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

EC De Bruin, N McGranahan, R Mitter, M Salm… - Science, 2014 - science.org
Spatial and temporal dissection of the genomic changes occurring during the evolution of
human non–small cell lung cancer (NSCLC) may help elucidate the basis for its dismal …

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

MG Kris, BE Johnson, LD Berry, DJ Kwiatkowski… - Jama, 2014 - jamanetwork.com
Importance Targeting oncogenic drivers (genomic alterations critical to cancer development
and maintenance) has transformed the care of patients with lung adenocarcinomas. The …

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

E Collisson, J Campbell, A Brooks, A Berger, W Lee… - Nature, 2014 - espace.curtin.edu.au
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …

[HTML][HTML] Pan-cancer patterns of somatic copy number alteration

TI Zack, SE Schumacher, SL Carter, AD Cherniack… - Nature …, 2013 - nature.com
Determining how somatic copy number alterations (SCNAs) promote cancer is an important
goal. We characterized SCNA patterns in 4,934 cancers from The Cancer Genome Atlas …

The somatic genomic landscape of chromophobe renal cell carcinoma

CF Davis, CJ Ricketts, M Wang, L Yang, AD Cherniack… - Cancer cell, 2014 - cell.com
We describe the landscape of somatic genomic alterations of 66 chromophobe renal cell
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive …