[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …
[HTML][HTML] Lessons from the cancer genome
LA Garraway, ES Lander - Cell, 2013 - cell.com
Systematic studies of the cancer genome have exploded in recent years. These studies
have revealed scores of new cancer genes, including many in processes not previously …
have revealed scores of new cancer genes, including many in processes not previously …
Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …
[HTML][HTML] Defining a cancer dependency map
Most human epithelial tumors harbor numerous alterations, making it difficult to predict
which genes are required for tumor survival. To systematically identify cancer dependencies …
which genes are required for tumor survival. To systematically identify cancer dependencies …
[HTML][HTML] Comprehensive molecular profiling of lung adenocarcinoma
Cancer Genome Atlas Research Network - Nature, 2014 - ncbi.nlm.nih.gov
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC De Bruin, N McGranahan, R Mitter, M Salm… - Science, 2014 - science.org
Spatial and temporal dissection of the genomic changes occurring during the evolution of
human non–small cell lung cancer (NSCLC) may help elucidate the basis for its dismal …
human non–small cell lung cancer (NSCLC) may help elucidate the basis for its dismal …
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
MG Kris, BE Johnson, LD Berry, DJ Kwiatkowski… - Jama, 2014 - jamanetwork.com
Importance Targeting oncogenic drivers (genomic alterations critical to cancer development
and maintenance) has transformed the care of patients with lung adenocarcinomas. The …
and maintenance) has transformed the care of patients with lung adenocarcinomas. The …
Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …
[HTML][HTML] Pan-cancer patterns of somatic copy number alteration
Determining how somatic copy number alterations (SCNAs) promote cancer is an important
goal. We characterized SCNA patterns in 4,934 cancers from The Cancer Genome Atlas …
goal. We characterized SCNA patterns in 4,934 cancers from The Cancer Genome Atlas …
The somatic genomic landscape of chromophobe renal cell carcinoma
We describe the landscape of somatic genomic alterations of 66 chromophobe renal cell
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive …
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive …