Guide to metabolomics analysis: a bioinformatics workflow

Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

Mass spectrometric based approaches in urine metabolomics and biomarker discovery

MM Khamis, DJ Adamko… - Mass spectrometry …, 2017 - Wiley Online Library
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

P Qu, O Rom, K Li, L Jia, X Gao, Z Liu, S Ding, M Zhao… - Cell metabolism, 2023 - cell.com
Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy
approved. A major hurdle in NASH drug development is the poor translatability of preclinical …

Altered gut microbial metabolites in amnestic mild cognitive impairment and Alzheimer's disease: signals in host–microbe interplay

L Wu, Y Han, Z Zheng, G Peng, P Liu, S Yue, S Zhu… - Nutrients, 2021 - mdpi.com
Intimate metabolic host–microbiome crosstalk regulates immune, metabolic, and neuronal
response in health and disease, yet remains untapped for biomarkers or intervention for …

XCMS Online: a web-based platform to process untargeted metabolomic data

R Tautenhahn, GJ Patti, D Rinehart… - Analytical …, 2012 - ACS Publications
Recently, interest in untargeted metabolomics has become prevalent in the general scientific
community among an increasing number of investigators. The majority of these …

Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics

Q Huang, Y Tan, P Yin, G Ye, P Gao, X Lu, H Wang… - Cancer research, 2013 - AACR
Hepatocellular carcinoma has a poor prognosis due to its rapid development and early
metastasis. In this report, we characterized the metabolic features of hepatocellular …

HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS

DQ Tang, L Zou, XX Yin, CN Ong - Mass spectrometry reviews, 2016 - Wiley Online Library
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …

FeOOH@ metal–organic framework core–satellite nanocomposites for the serum metabolic fingerprinting of gynecological cancers

C Pei, C Liu, Y Wang, D Cheng, R Li, W Shu… - Angewandte …, 2020 - Wiley Online Library
High‐throughput metabolic analysis is of significance in diagnostics, while tedious sample
pretreatment has largely hindered its clinic application. Herein, we designed FeOOH@ ZIF …

Untargeted LC/MS-based metabolic phenotyping (metabonomics/metabolomics): The state of the art

H Gika, C Virgiliou, G Theodoridis, RS Plumb… - … of Chromatography B, 2019 - Elsevier
Liquid chromatography (LC) hyphenated to mass spectrometry is currently the most widely
used means of determining metabolic phenotypes via both untargeted and targeted …

Untargeted and Targeted Discrimination of Honey Collected by Apis cerana and Apis mellifera Based on Volatiles Using HS-GC-IMS and HS-SPME-GC–MS

X Wang, KM Rogers, Y Li, S Yang… - Journal of Agricultural …, 2019 - ACS Publications
Fraudulent acts regarding honey authenticity that use Apis mellifera honey as a substitute for
Apis cerana honey have garnered considerable concern in China and triggered a trust crisis …