The role of zinc in male fertility

D Allouche-Fitoussi, H Breitbart - International journal of molecular …, 2020 - mdpi.com
Several studies proposed the importance of zinc ion in male fertility. Here, we describe the
properties, roles and cellular mechanisms of action of Zn2+ in spermatozoa, focusing on its …

Transcription factors and transporters in zinc homeostasis: lessons learned from fungi

DJ Eide - Critical reviews in biochemistry and molecular biology, 2020 - Taylor & Francis
Zinc is an essential nutrient for all organisms because this metal serves as a critical
structural or catalytic cofactor for many proteins. These zinc-dependent proteins are …

Long-term and low-dose exposure to nanopolystyrene induces a protective strategy to maintain functional state of intestine barrier in nematode Caenorhabditis …

H Shao, D Wang - Environmental Pollution, 2020 - Elsevier
Functional state of intestinal barrier plays an important role for environmental animals in
being against various toxicants. We investigated GATA transcriptional factor ELT-2-mediated …

Orsay Virus infection of Caenorhabditis elegans is modulated by zinc and dependent on lipids

LA Casorla-Perez, R Guennoun, C Cubillas… - Journal of …, 2022 - Am Soc Microbiol
Viruses utilize host lipids to promote the viral life cycle, but much remains unknown as to
how this is regulated. Zinc is a critical element for life, and few studies have linked zinc to …

Zinc homeostasis may reverse the synergistic neurotoxicity of heavy metal mixtures in Caenorhabditis elegans

H Cai, Y Bao, H Cheng, X Ge, M Zhang, X Feng… - Science of The Total …, 2023 - Elsevier
Heavy metal mixtures can cause nerve damage. However, the combined effects of metal
mixtures are extremely complex and rarely studied. Zinc (Zn) homeostasis plays an integral …

Endoplasmic Reticulum Stress/Ca2+-Calmodulin-Dependent Protein Kinase/Signal Transducer and Activator of Transcription 3 Pathway Plays a Role in the …

H Zhao, D Liu, Q Yan, X Bian, J Yu, J Wang… - Frontiers in …, 2022 - frontiersin.org
Zinc homeostasis has been known to play a role in myocardial ischemia/reperfusion (I/R)
injury, but the precise molecular mechanisms regulating the expression of ZIP transporters …

The zinc transporter ZIPT-7.1 regulates sperm activation in nematodes

Y Zhao, CH Tan, A Krauchunas, A Scharf… - PLoS …, 2018 - journals.plos.org
Sperm activation is a fascinating example of cell differentiation, in which immotile spermatids
undergo a rapid and dramatic transition to become mature, motile sperm. Because the …

Oral elesclomol treatment alleviates copper deficiency in animal models

S Yuan, T Korolnek, BE Kim - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Copper (Cu) is an essential trace element for key biochemical reactions. Dietary or genetic
copper deficiencies are associated with anemia, cardiomyopathy, and neurodegeneration …

Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans

KS Evans, S Zdraljevic, L Stevens, K Collins… - PLoS …, 2020 - journals.plos.org
Zinc is an essential trace element that acts as a co-factor for many enzymes and
transcription factors required for cellular growth and development. Altering intracellular zinc …

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

EM Chapman, B Lant, Y Ohashi, B Yu… - Nature …, 2019 - nature.com
Apoptotic death of cells damaged by genotoxic stress requires regulatory input from
surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian …