Adiponectin: role in physiology and pathophysiology

TMD Nguyen - International journal of preventive medicine, 2020 - journals.lww.com
Background: Chronic diseases such as diabetes have an adverse effect on the quality of life
(QOL) of patients. It has been shown physical activity can improve the quality of life. Aims …

Chicken is a useful model to investigate the role of adipokines in metabolic and reproductive diseases

N Mellouk, C Ramé, A Barbe… - International journal …, 2018 - Wiley Online Library
Reproduction is a complex and essential physiological process required by all species to
produce a new generation. This process involves strict hormonal regulation, depending on a …

Ovarian cancer: applications of chickens to humans

A Barua, JM Bahr - Annual review of animal biosciences, 2022 - annualreviews.org
The lack of preclinical models of spontaneous ovarian cancer (OVCA), a fatal gynecological
malignancy, is a significant barrier to generating information on early changes indicative of …

Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells

AA Ramzan, BG Bitler, D Hicks, K Barner… - Molecular and Cellular …, 2019 - Springer
We tested the hypothesis that stimulation of adiponectin receptors with the synthetic agonist
AdipoRon suppresses proliferation and induces apoptotic death in human high grade …

Adipokines in metabolic and reproductive functions in birds: An overview of current knowns and unknowns

O Bernardi, A Estienne, M Reverchon, Y Bigot… - Molecular and Cellular …, 2021 - Elsevier
Adipose tissue is now recognized as an active endocrine organ, which synthesizes and
secretes numerous peptides factors called adipokines. In mammals, they exert pleiotropic …

Adipokines expression and effects in oocyte maturation, fertilization and early embryo development: lessons from mammals and birds

A Estienne, A Brossaud, M Reverchon, C Ramé… - International Journal of …, 2020 - mdpi.com
Some evidence shows that body mass index in humans and extreme weights in animal
models, including avian species, are associated with low in vitro fertilization, bad oocyte …

Obesity and energy substrate transporters in ovarian cancer

M Baczewska, K Bojczuk, A Kołakowski, J Dobroch… - Molecules, 2021 - mdpi.com
Ovarian cancer is the seventh most common cancer in women. It is characterized by a high
mortality rate because of its aggressiveness and advanced stage at the time of diagnosis. It …

Adiponectin reverses the proliferative effects of estradiol and IGF-1 in human epithelial ovarian cancer cells by downregulating the expression of their receptors

M Hoffmann, J Gogola, A Ptak - Hormones and Cancer, 2018 - Springer
The expression of adiponectin receptors AdipoR1 and AdipoR2 has been reported in the
human ovary and ovarian cancer tissues. Moreover, adiponectin has been reported to act as …

A Bioinformatics Analysis of Ovarian Cancer Data Using Machine Learning

V Schilling, P Beyerlein, J Chien - Algorithms, 2023 - mdpi.com
The identification of biomarkers is crucial for cancer diagnosis, understanding the underlying
biological mechanisms, and developing targeted therapies. In this study, we propose a …

[HTML][HTML] Expression of adiponectin receptor-1 and prognosis of epithelial ovarian cancer patients

X Li, Z Yu, L Fang, F Liu, K Jiang - Medical Science Monitor …, 2017 - ncbi.nlm.nih.gov
Background Adiponectin receptor-1 (AdipoR1) has been reported to be associated with the
risk of obesity-associated malignancies, including epithelial ovarian cancer (EOC). The aim …