The immune system is coordinated by an intricate network of stimulatory and inhibitory
circuits that regulate host responses against endogenous and exogenous insults. Disruption …

Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic dysregulated response to alveolar
epithelial injury with differentiation of epithelial cells and fibroblasts into matrix-secreting …

The function of deciphering the biological information encoded by the glycome, which is the
entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in …

Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …

Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …

Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …

Regulatory signals provide negative input to immunological networks promoting resolution
of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily …

Galectins, β‐galactoside‐binding animal lectins, are differentially expressed by various
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …

Regulated glycosylation controls T cell processes, including activation, differentiation and
homing by creating or masking ligands for endogenous lectins. Here we show that stimuli …