Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

New evidence has stirred up a long‐standing but undeservedly forgotten interest in the role
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …

In contrast to an obsolete notion that erythrocytes, or red blood cells (RBC s), play a passive
and minor role in haemostasis and thrombosis, over the past decades there has been …

Red cell transfusion therapy is a common treatment modality in contemporary medical
practice. Although blood collection and administration is safer and more efficient than ever …

Purpose Cardiopulmonary bypass induces an ischaemia–reperfusion injury and systemic
inflammatory response, which contributes to low cardiac output syndrome following cardiac …

The collection and storage of red blood cells (RBCs) is a logistical necessity to provide
sufficient blood products. However, RBC storage is an unnatural state, resulting in …

Transfusion of blood cell components is frequent in the therapeutic arsenal; it is globally safe
or even very safe. At present, residual clinical manifestations are principally inflammatory in …

Red blood cell (RBC) transfusion is a life-saving treatment for several pathologies. RBCs for
transfusion are stored refrigerated in a preservative solution, which extends their shelf-life for …

Microparticles are small membrane-bound vesicles found in body fluids including peripheral
blood. Microparticles are an intrinsic part of blood labile products delivered to transfused …

Numerous retrospective clinical studies suggest that transfusion of longer stored red blood
cells (RBCs) is associated with an independent risk of poorer outcomes for certain groups of …