Aminoglycoside antibiotics, in particular gentamicin and tobramycin, are still commonly used
in paediatric clinical practice. These drugs cause nephrotoxicity, which particularly affects …

Recurrent and chronic bacterial infections are common in people with cystic fibrosis (CF)
and contribute to lung function decline. Antibiotics are the mainstay in the treatment of …

This is the third in a series of four papers updating the European Cystic Fibrosis Society
(ECFS) standards for the care of people with CF. This paper focuses on recognising and …

The contribution of nephrotoxic medications to the development of acute kidney injury (AKI)
is becoming better understood concomitant with the increased incidence of AKI in children …

The outcome of acute kidney injury (AKI) as a result of aminoglycosides (AGs) use remains
uncertain in patients without prior chronic kidney disease (CKD). Therefore, we explored the …

Objective: Interruptive acute kidney injury alerts are reported to decrease acute kidney injury–
related mortality in adults. Critically ill children have multiple acute kidney injury risk factors; …

Introduction Further optimization of therapeutic drug monitoring (TDM) for aminoglycosides
(AGs) is urgently needed, especially in special populations such as those with cystic fibrosis …

Cystic fibrosis (CF) patients, with Pseudomonas aeruginosa infection, often require repeated
aminoglycoside courses for the management of acute pulmonary exacerbations (APEs) …

Background: Infection and its treatment as a common problem in children may induce
different complications. Ampicillin and aminoglycosides, as choice drugs for this condition …

Background Vancomycin-induced acute kidney injury (VI-AKI) is one of its serious adverse
reactions. The purpose of this study is to discuss the risk factors for VI-AKI in overweight …