The species tree paradigm that dominates current molecular systematic practice infers
species trees from collections of sequences under assumptions of the multispecies …

The mitonuclear genome is the most successful co-evolved mutualism in the history of life on
Earth. The cross-talk between the mitochondrial and nuclear genomes has been shaped by …

The genus Saccharomyces is an evolutionary paradox. On the one hand, it is composed of
at least eight clearly phylogenetically delineated species; these species are reproductively …

A growing body of research suggests that the mitochondrial genome (mtDNA) is important
for temperature adaptation. In the yeast genus Saccharomyces, species have diverged in …

Recent advances in long-read sequencing technology have allowed for single-molecule
sequencing of entire mitochondrial genomes, opening the door for direct investigation of the …

Genetic analysis of phenotypic differences between species is typically limited to interfertile
species. Here, we conducted a genome-wide noncomplementation screen to identify genes …

The molecular basis of how temperature affects cell metabolism has been a long-standing
question in biology, where the main obstacles are the lack of high-quality data and methods …

An unknown interspecies Saccharomyces hybrid,“Muri,” was recently isolated from a “kveik”
culture, a traditional Norwegian farmhouse brewing yeast culture. Here we used whole …

Critical mitochondrial functions, including cellular respiration, rely on frequently interacting
components expressed from both the mitochondrial and nuclear genomes. The fitness of …

Proteins are the workhorses of the cell and execute many of their functions by interacting
with other proteins forming protein complexes. Multi-protein complexes are an admixture of …