CD44: a multifunctional mediator of cancer progression
CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
Nanoparticle-based drug delivery systems targeting cancer cell surfaces
L Hong, W Li, Y Li, S Yin - RSC advances, 2023 - pubs.rsc.org
Traditional cancer chemotherapy easily produces serious toxic and side effects due to the
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
Current Perspectives on 89Zr-PET Imaging
JK Yoon, BN Park, EK Ryu, YS An, SJ Lee - International Journal of …, 2020 - mdpi.com
89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …
Recent progress in the early detection of cancer based on CD44 biomarker; nano-biosensing approaches
CD44 is a cell matrix adhesion molecule overexpressed on the cell surfaces of the major
cancers. CD44 as a cancer-related biomarker has an essential role in the invasion and …
cancers. CD44 as a cancer-related biomarker has an essential role in the invasion and …
[HTML][HTML] Changes in protein glycosylation in head and neck squamous cell carcinoma
C Liao, J An, Z Tan, F Xu, J Liu, Q Wang - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Glycosylation is an important posttranslational modification of proteins, and it has a profound
influence on diverse life processes. An abnormal polysaccharide structure and mutation of …
influence on diverse life processes. An abnormal polysaccharide structure and mutation of …
A Novel Anti-CD44 Variant 9 Monoclonal Antibody C44Mab-1 Was Developed for Immunohistochemical Analyses against Colorectal Cancers
M Tawara, H Suzuki, N Goto, T Tanaka… - Current Issues in …, 2023 - mdpi.com
Cluster of differentiation 44 (CD44) is a type I transmembrane glycoprotein and has been
shown to be a cell surface marker of cancer stem-like cells in various cancers. In particular …
shown to be a cell surface marker of cancer stem-like cells in various cancers. In particular …
Liquid biopsy and circulating biomarkers for the diagnosis of precancerous and cancerous oral lesions
Oral cancer is one of the most common malignancies worldwide, accounting for 2% of all
cases annually and 1.8% of all cancer deaths. To date, tissue biopsy and histopathological …
cases annually and 1.8% of all cancer deaths. To date, tissue biopsy and histopathological …
CD44: a cancer stem cell marker and therapeutic target in leukemia treatment
S Wu, Y Tan, F Li, Y Han, S Zhang, X Lin - Frontiers in Immunology, 2024 - frontiersin.org
CD44 is a ubiquitous leukocyte adhesion molecule involved in cell-cell interaction, cell
adhesion, migration, homing and differentiation. CD44 can mediate the interaction between …
adhesion, migration, homing and differentiation. CD44 can mediate the interaction between …
Roles and mechanisms of aberrant alternative splicing in melanoma—implications for targeted therapy and immunotherapy resistance
W Chen, D Geng, J Chen, X Han, Q Xie, G Guo… - Cancer Cell …, 2024 - Springer
Background Despite advances in therapeutic strategies, resistance to immunotherapy and
the off-target effects of targeted therapy have significantly weakened the benefits for patients …
the off-target effects of targeted therapy have significantly weakened the benefits for patients …
Development of a Novel Anti-CD44 Variant 8 Monoclonal Antibody C44Mab-94 against Gastric Carcinomas
H Suzuki, N Goto, T Tanaka, T Ouchida, MK Kaneko… - Antibodies, 2023 - mdpi.com
Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. GC with
peritoneal metastasis exhibits a poor prognosis due to the lack of effective therapy. A …
peritoneal metastasis exhibits a poor prognosis due to the lack of effective therapy. A …