Obesity remains a global health problem. Chronic low-grade inflammation in this pathology
has been related to comorbidities such as cognitive alterations that, in the long term, can …

Introduction The implications of maternal overnutrition on offspring metabolic and
neuroimmune development are well-known. Increasing evidence now suggests that …

Advances in omics and microbiome technology have transformed the ways in which the
biological consequences of life in the 'ecological theatre'can be visualized. Exposome …

Recent studies have demonstrated the intimate relationship between depression and
immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the …

Ivermectin (IVM) is an antiparasitic agent widely used in agricultural, domestic animals and
in human clinical practice. In the present study, the temporal effects of therapeutic doses of …

Aims This study investigated the possible relationships between the expression of the Kiss1
and Gpr54 gene expressions and the pituitary-gonadal hormones with the female onset of …

Considering all mental and addictive disorders, depression is the most responsible for years
of life lost due to premature mortality and disability. Antidepressant drugs have limited …

Introduction: Obesity promotes hypothalamic inflammation and local morphological changes
in astrocytes, including the increased expression of the astrocytic biomarker glial fibrillary …

While metabolic disorders such as obesity and diabetes are costly and deadly to the current
population, they are also extremely detrimental to the next generation. Much of the current …

Changes in the in utero environment result in generational transfer of maladapted
physiology in the context of conditions such as stress, obesity, and anxiety. Given the …