[HTML][HTML] Emerging roles of lysophospholipids in health and disease
ST Tan, T Ramesh, XR Toh, LN Nguyen - Progress in Lipid Research, 2020 - Elsevier
Lipids are abundant and play essential roles in human health and disease. The main
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …
[HTML][HTML] Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer
J Huang, J Wang, H He, Z Huang, S Wu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Abnormal lipid metabolism including synthesis, uptake, modification, degradation and
transport has been considered a hallmark of malignant tumors and contributes to the supply …
transport has been considered a hallmark of malignant tumors and contributes to the supply …
METTL3-mediated m6A methylation of SPHK2 promotes gastric cancer progression by targeting KLF2
FC Huo, ZM Zhu, WT Zhu, QY Du, J Liang, J Mou - Oncogene, 2021 - nature.com
Abstract N6-methyladenosine (m6A) RNA methylation is profoundly involved in epigenetic
regulation, especially for carcinogenesis and tumor progression. Mounting evidence …
regulation, especially for carcinogenesis and tumor progression. Mounting evidence …
Sphingosine 1‐phosphate liposomes for targeted nitric oxide delivery to mediate anticancer effects against brain glioma tumors
Specifically targeting glioblastoma multiforme (GBM) blood vessels and actively enhancing
the permeability of the brain–blood–tumor barrier (BBTB) are two extremely difficult …
the permeability of the brain–blood–tumor barrier (BBTB) are two extremely difficult …
[HTML][HTML] Targeting the sphingosine kinase/sphingosine-1-phosphate signaling axis in drug discovery for cancer therapy
Simple Summary Cancer is the prime cause of death globally. The altered stimulation of
signaling pathways controlled by human kinases has often been observed in various human …
signaling pathways controlled by human kinases has often been observed in various human …
[HTML][HTML] The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target
SS Alkafaas, MI Elsalahaty, DF Ismail… - Cancer Cell …, 2024 - Springer
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous
cancer management protocols. It can promote cancer recurrence, spreading of cancer, and …
cancer management protocols. It can promote cancer recurrence, spreading of cancer, and …
Genomics and transcriptomics: the powerful technologies in precision medicine
A Khodadadian, S Darzi, S Haghi-Daredeh… - … Journal of General …, 2020 - Taylor & Francis
In a clinical trial, people with the same disease can show different responses after treatment
with the same drug and exactly under the same conditions. Some of them may improve …
with the same drug and exactly under the same conditions. Some of them may improve …
[HTML][HTML] The role of KLF transcription factor in the regulation of cancer progression
ZY Li, YX Zhu, JR Chen, X Chang, ZZ Xie - Biomedicine & …, 2023 - Elsevier
Kruppel-like factors (KLFs) are a family of zinc finger transcription factors that have been
found to play an essential role in the development of various human tissues, including …
found to play an essential role in the development of various human tissues, including …
Recent advances in iron oxide nanoparticles for brain cancer theranostics: from in vitro to clinical applications
Introduction: Today, the development of multifunctional nanoplatforms is more seriously
considered in the field of cancer theranostics. Areas covered: In this respect, nanoparticles …
considered in the field of cancer theranostics. Areas covered: In this respect, nanoparticles …
[HTML][HTML] Follicle-stimulating hormone promotes the proliferation of epithelial ovarian cancer cells by activating sphingosine kinase
K Song, L Dai, X Long, W Wang, W Di - Scientific reports, 2020 - nature.com
Follicle-stimulating hormone (FSH) is closely related to the pathogenesis and progression of
epithelial ovarian cancer (EOC). However, until now, knowledge relating to FSH-driven …
epithelial ovarian cancer (EOC). However, until now, knowledge relating to FSH-driven …