Milk has two main components that have high nutritional value—milk protein (casein and
whey protein), and lactose. These components are extensively used in various areas …

Studies of active drug/excipient compatibility represent an important phase in the
preformulation stage of the development of all dosage forms. The potential physical and …

This review summarizes the current knowledge on anatomy and physiology of the human
gastrointestinal tract in comparison with that of common laboratory animals (dog, pig, rat and …

A simple, rapid, precise and accurate isocratic reversed-phase stability-indicating HPLC
method was developed and validated for the simultaneous determination of atorvastatin (AT) …

Drug-excipient interactions in solid dosage forms can affect drug product stability in physical
aspects such as organoleptic changes and dissolution slowdown, or chemically by causing …

This study documents drug–excipient incompatibility studies of acyclovir in physical mixtures
with lactose and in different tablet brands. Differential scanning calorimetry (DSC) was …

The objective of the current research article is to provide a comprehensive review of
excipients impact on the stability of the drug product and their implications during the …

Curdlan has been considered as a promising food additive and eventually utilized in the
fabrication of several drug delivery systems. But it has not been developed and utilized in …

Lactose is present as an excipient in nearly half of all solid medicines. Despite the
assumption of chemical stability, in aqueous solution, the chiral composition of lactose is …

The objective of ICH Q8, Q9 and Q10 documents is application of systemic and science
based approach to formulation development for building quality into product. There is …