Purification and Characterization of Glutaminase Free Asparaginase from Enterobacter cloacae: In-Vitro Evaluation of Cytotoxic Potential against Human Myeloid …

I Husain, A Sharma, S Kumar, F Malik - PLoS One, 2016 - journals.plos.org
Asparaginase is an important antileukemic agent extensively used worldwide but the
intrinsic glutaminase activity of this enzymatic drug is responsible for serious life threatening …

Purification and characterization of glutaminase free asparaginase from Pseudomonas otitidis: Induce apoptosis in human leukemia MOLT-4 cells

I Husain, A Sharma, S Kumar, F Malik - Biochimie, 2016 - Elsevier
Asparaginase is an important antineoplastic drug extensively used for the treatment of acute
lymphoblastic leukemia, but the intrinsic glutaminase activity of this enzymatic drug is …

[PDF][PDF] Optimization of medium components for extracellular glutaminase free asparaginase from Enterobacter cloacae

A Sharma, I Husain - Int J Curr Microbiol App Sci, 2015 - researchgate.net
Bacterial asparaginase (L-Asparaginase amidohydrolase, EC 3.5. 1.1) is a selective and
highly effective chemotherapeutic agent extensively used over the world in first-line …

Preliminary evaluation of arginine deiminase activity of indigenous bacterial strains for suitable chemotherapeutic applications

A Sharma, K Bala, I Husain - Biocatalysis and Agricultural Biotechnology, 2017 - Elsevier
Cancer is one of the most detrimental disease affects significant segment of human
population. Arginine deiminase (ADI) is an anticancer enzyme used in chemotherapy of …

Arginine deaminase from Pseudomonas aeruginosa PS2: purification, biochemical characterization and in-vitro evaluation of anticancer activity

K Bala, I Husain, A Sharma - 3 Biotech, 2020 - Springer
In the present study, arginine deaminase (ADI) was purified from Pseudomonas aeruginosa
PS2 which showed relative molecular mass of 70±3 kDa on native-PAGE and 36±0.5 kDa …

Optimizing arginine deiminase production from Pseudomonas aeruginosa clinical isolate

RA Ibrahim, AA Hussein… - … Sciences and Research, 2019 - search.proquest.com
Biochemical tests The suspected isolates were subjected to the biochemical tests as
mentioned by (8), and as follow: A Catalase test A single colony of each bacterial isolate …

[PDF][PDF] Optimization of arginine deaminase production from indigenous bacterium Pseudomonas aeruginosa PS2

A Sharma, K Bala, I Husain - Int J Curr Microbiol Appl Sci, 2017 - academia.edu
A molecule of biological origin has great importance and plays a critical role in sustaining of
life on earth. Proteins and peptides are the important class of biomolecules possesses …

Production of anti-leukemia L-Asparaginase by a strain of Staphylococcus Isolated from Agricultural Soil

M Ghorbanmovahed, G Ebrahimipour… - … of Medical Sciences, 2016 - jmums.mazums.ac.ir
Background and purpose: L-asparaginase is a well-known enzyme that is used as one of
the most effective anti-leukemic drugs. Considering that the asparaginases used as …

[PDF][PDF] Process parameter optimization for asparaginase production from O. intermedium: A potential candidate for acrylamide mitigation

A Sharma, S Mishra - Int. J. Curr. Microbiol. App. Sci, 2017 - academia.edu
Acrylamide (C3H5NO) is a toxic aliphatic amide compound, usually formed industrially from
the hydration of acrylonitrile. The occurrences of acrylamide during heating above 120 C in …

Pseudomonas montielli-A Potent Chemotherapeutic Asparaginase producing organism Isolated from Rhizosphere Soil

A Subhashini, GS Vani - Research Journal of Pharmacy and …, 2020 - indianjournals.com
The enzyme Asparaginase finds its extensive application in chemotherapeutic as well as in
food manufacturing industries on a large scale. Prolonged use of the enzyme from a single …