Targeted alpha therapy using Radium-223: From physics to biological effects

IA Marques, AR Neves, AM Abrantes, AS Pires… - Cancer treatment …, 2018 - Elsevier
With the advance of the use of ionizing radiation in therapy, targeted alpha therapy (TAT)
has assumed an important role around the world. This kind of therapy can potentially reduce …

Ascorbic acid chemosensitizes colorectal cancer cells and synergistically inhibits tumor growth

AS Pires, CR Marques, JC Encarnação… - Frontiers in …, 2018 - frontiersin.org
Colorectal cancer (CRC) is continuously classified as one of the most incidental and mortal
types of cancer worldwide. The positive outcomes of the conventional chemotherapy are …

Kinetics of radium-223 and its effects on survival, proliferation and DNA damage in lymph-node and bone metastatic prostate cancer cell lines

IA Marques, AM Abrantes, AS Pires… - … Journal of Radiation …, 2021 - Taylor & Francis
Background Metastatic castration-resistant prostate cancer (mCRPC) is associated with a
very unfavorable prognosis. At this advanced stage of the disease, there are several …