Adrenocortical zonation, renewal, and remodeling
M Pihlajoki, J Dörner, RS Cochran… - Frontiers in …, 2015 - frontiersin.org
The adrenal cortex is divided into concentric zones. In humans the major cortical zones are
the zona glomerulosa, zona fasciculata, and zona reticularis. The adrenal cortex is a …
the zona glomerulosa, zona fasciculata, and zona reticularis. The adrenal cortex is a …
Future directions for adrenal insufficiency: cellular transplantation and genetic therapies
Primary adrenal insufficiency (PAI) occurs in 1 in 5 to 7000 adults. Leading etiologies are
autoimmune adrenalitis in adults and congenital adrenal hyperplasia (CAH) in children. Oral …
autoimmune adrenalitis in adults and congenital adrenal hyperplasia (CAH) in children. Oral …
Functional implications of LH/hCG receptors in pregnancy-induced Cushing syndrome
U Plöckinger, M Chrusciel, M Doroszko… - Journal of the …, 2017 - academic.oup.com
Context: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed
luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy …
luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy …
GLI1+ progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue
J Dörner, VM Rodriguez, R Ziegler, T Röhrig… - Molecular and cellular …, 2017 - Elsevier
As certain strains of mice age, hyperplastic lesions resembling gonadal tissue accumulate
beneath the adrenal capsule. Gonadectomy (GDX) accelerates this heterotopic …
beneath the adrenal capsule. Gonadectomy (GDX) accelerates this heterotopic …
GATA factors in endocrine neoplasia
GATA transcription factors are structurally-related zinc finger proteins that recognize the
consensus DNA sequence WGATAA (the GATA motif), an essential cis-acting element in the …
consensus DNA sequence WGATAA (the GATA motif), an essential cis-acting element in the …
miR-126 affects the invasion and migration of glioma cells through GATA4
Y Xu, W Xu, T Lu, Y Dai, W Liang - Artificial Cells, Nanomedicine …, 2017 - Taylor & Francis
We aimed to explore the relationship between miR-126 and glioma. miR-126 was highly
expressed in low-grade clinical glioma tissue samples but lowly expressed in high-grade …
expressed in low-grade clinical glioma tissue samples but lowly expressed in high-grade …
[HTML][HTML] Current insight into the transient X-zone in the adrenal gland cortex
Y Kang, K Laprocina, HS Zheng… - Vitamins and …, 2024 - ncbi.nlm.nih.gov
Mouse models have been widely used in the study of adrenal gland development and
diseases. The X-zone is a unique structure of the mouse adrenal gland and lineage-tracing …
diseases. The X-zone is a unique structure of the mouse adrenal gland and lineage-tracing …
Mouse models of adrenocortical tumors
KJ Basham, HA Hung, AM Lerario… - Molecular and cellular …, 2016 - Elsevier
The molecular basis of the organogenesis, homeostasis, and tumorigenesis of the adrenal
cortex has been the subject of intense study for many decades. Specifically, characterization …
cortex has been the subject of intense study for many decades. Specifically, characterization …
Probing GATA factor function in mouse Leydig cells via testicular injection of adenoviral vectors
GM Penny, RB Cochran, M Pihlajoki… - …, 2017 - rep.bioscientifica.com
Testicular Leydig cells produce androgens essential for proper male reproductive
development and fertility. Here, we describe a new Leydig cell ablation model based on …
development and fertility. Here, we describe a new Leydig cell ablation model based on …
Luteinizing hormone and GATA4 action in the adrenocortical tumorigenesis of gonadectomized female mice
M Doroszko, M Chrusciel, J Stelmaszewska… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Physiological role of luteinizing hormone (LH) and its receptor
(LHCGR) in adrenal remains unknown. In inhibin-α/Simian Virus 40 T antigen …
(LHCGR) in adrenal remains unknown. In inhibin-α/Simian Virus 40 T antigen …