Noninvasive magnetic resonance imaging measures of glymphatic system activity

K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

Imaging interstitial fluid with MRI: a narrative review on the associations of altered interstitial fluid with vascular and neurodegenerative abnormalities

GS Drenthen, EP Elschot… - Journal of Magnetic …, 2024 - Wiley Online Library
Interstitial fluid (ISF) refers to the fluid between the parenchymal cells and along the
perivascular spaces (PVS). ISF plays a crucial role in delivering nutrients and clearing waste …

The association of the glymphatic function with Parkinson's disease symptoms: neuroimaging evidence from longitudinal and cross‐sectional studies

P He, L Shi, Y Li, Q Duan, Y Qiu, S Feng… - Annals of …, 2023 - Wiley Online Library
Objective Emerging pathological evidence suggests that there is an association between
glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the …

Glymphatic dysfunction in patients with early-stage amyotrophic lateral sclerosis

S Liu, X Sun, Q Ren, Y Chen, T Dai, Y Yang, G Gong… - Brain, 2024 - academic.oup.com
Recently, an astrocytic aquaporin 4-dependent drainage system, that is, the glymphatic
system, has been identified in the live murine and human brain. Growing evidence suggests …

Neuroimaging uncovers distinct relationships of glymphatic dysfunction and motor symptoms in Parkinson's disease

Y Qin, R He, J Chen, X Zhou, X Zhou, Z Liu, Q Xu… - Journal of …, 2023 - Springer
Background Studies of glymphatic dysfunction in Parkinson's disease (PD) patients have
attracted much attention in recent years. However, the relationships between glymphatic …

[HTML][HTML] Glymphatic function and its influencing factors in different glucose metabolism states

B Tian, C Zhao, JL Liang, HT Zhang… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Dysfunction of the glymphatic system in the brain in different stages of
altered glucose metabolism and its influencing factors are not well characterized. AIM To …

Increased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space

X Zhang, W Wang, X Bai, X Zhang, Z Yuan… - The Journal of …, 2023 - Springer
Background Preliminary evidence suggests that several headache disorders may be
associated with glymphatic dysfunction. However, no studies have been conducted to …

Age-and time-of-day dependence of glymphatic function in the human brain measured via two diffusion MRI methods

G Han, Y Zhou, K Zhang, B Jiao, J Hu… - Frontiers in Aging …, 2023 - frontiersin.org
Advanced age, accompanied by impaired glymphatic function, is a key risk factor for many
neurodegenerative diseases. To study age-related differences in the human glymphatic …

Diffusion tensor imaging‐along the perivascular‐space index is associated with disease progression in Parkinson's disease

KH Wood, R Nenert, AM Miften, GW Kent… - Movement …, 2024 - Wiley Online Library
Background The glymphatic clearance pathway is a waste clearance system that allows for
removal of soluble proteins such as amyloid β (Aβ) from the brain. Higher Aβ levels are …

Correlation of glymphatic system abnormalities with Parkinson's disease progression: a clinical study based on non-invasive fMRI

JC Meng, MQ Shen, YL Lu, HX Feng, XY Chen… - Journal of …, 2024 - Springer
Background The glymphatic system is reportedly involved in Parkinson's disease (PD).
Based on previous studies, we aimed to confirm the correlation between the glymphatic …