Many animal models have been developed to study the causes and treatments of chronic
kidney disease (CKD) in humans, an insidious disease resulting from kidney injury and …

Objectives: Whether uric acid levels were associated with the progression of chronic kidney
disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of …

Background Hyperuricemia is a putative risk factor for the progression of chronic kidney
disease (CKD). We hypothesized that control of asymptomatic hyperuricemia may slow …

Background Uremic toxicity may play a role in the elevated risk of developing cognitive
impairment found among patients with CKD. Some uremic toxins, like indoxyl sulfate, are …

High dietary fructose is an important causative factor in the development of metabolic
syndrome-associated glomerular podocyte oxidative stress and injury. Here, we identified …

Background/Aims: Epidemiological evidence indicates that patients with chronic kidney
diseases have increased susceptibility to adverse outcomes related to long-term exposure …

To date, good experimental animal models of renal anemia are not available. Therefore, the
purpose of this study was to establish a novel approach to induce chronic kidney disease …

Although poly (aspartic acid)(PASP), a strong calcium chelating agent, may be potentially
effective in inhibition of vascular calcification, its direct administration may lead to side …

With increasing prevalence, chronic kidney disease (CKD) has become a global health
problem. Due to the retention of uremic toxins, electrolytes and water, and the resultant …

Chronic kidney disease (CKD) is recognized as a global public health problem. NLRP3
inflammasome activation has been characterized to mediate diverse aspect mechanisms of …