The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …

Intestinal cancer is a heterogeneous disease driven by genetic mutations and epigenetic
changes. Approximately 80% of sporadic colorectal cancers are initiated by mutation and …

The anti-diabetic biguanide metformin may exert health-promoting effects via metabolic
regulation of the epigenome. Here we show that metformin promotes global DNA …

Extensive incorporation of engineered nanomaterials (ENMs) into industrial and biomedical
applications increases the risks of exposure to these potentially hazardous materials. While …

Inducible nitric oxide synthase (NOS2) produces high local concentrations of nitric oxide
(NO), and its expression is associated with inflammation, cellular stress signals, and cellular …

Within the last few decades, melatonin has increasingly emerged in clinical oncology as a
naturally occurring bioactive molecule with substantial anticancer properties and a …

Evidence continues to grow on potential environmental health hazards associated with
engineered nanomaterials (ENMs). While the geno-and cytotoxic effects of ENMs have been …

Background Methionine, a central molecule in one-carbon metabolism, is an essential
amino acid required for normal growth and development. Despite its importance to …