[HTML][HTML] Multiscale computational model predicts how environmental changes and drug treatments affect microvascular remodeling in fibrotic disease

J Leonard-Duke, SMJ Agro, DJ Csordas, AC Bruce… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Investigating the molecular, cellular, and tissue-level changes caused by disease, and the
effects of pharmacological treatments across these biological scales, necessitates the use of …

Genetic burden of dysregulated cytoskeletal organisation in the pathogenesis of pulmonary fibrosis

D Wang, Y Ni, B Liu, H Ding, A John, LV Wain… - bioRxiv, 2024 - biorxiv.org
Background Pulmonary fibrosis (PF) is a shared characteristic of chronic interstitial lung
diseases of mixed aetiology. Previous studies on PF highlight a pathogenic role for common …

Race, Telomeres, and Genomic Insights Into Pulmonary Fibrosis

AO Adegunsoye - 2023 - search.proquest.com
Pulmonary fibrosis pathophysiology is increasingly recognized to be influenced by the
biology of telomeres, a field that has now grown in prominence with the widespread …