[HTML][HTML] The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria

K Khalid, CL Poh - Vaccines, 2023 - mdpi.com
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

A critical review of novel antibiotic resistance prevention approaches with a focus on postbiotics

MA Ozma, SR Moaddab, H Hosseini… - Critical reviews in …, 2023 - Taylor & Francis
Antibiotic resistance is a significant public health issue, causing illnesses that were once
easily treatable with antibiotics to develop into dangerous infections, leading to substantial …

Skin microbiome dysbiosis and the role of Staphylococcus aureus in atopic dermatitis in adults and children: A narrative review

AL Demessant‐Flavigny, S Connétable… - Journal of the …, 2023 - Wiley Online Library
A dysfunctional epidermal barrier, which may be associated with mutations in the filaggrin
gene in genetically predisposed individuals or harmful effects of environmental agents and …

[HTML][HTML] Anti-inflammatory metabolites in the pathogenesis of bacterial infection

A Urso, A Prince - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Host and pathogen metabolism have a major impact on the outcome of infection. The
microenvironment consisting of immune and stromal cells drives bacterial proliferation and …

Vaccines and monoclonal antibodies as alternative strategies to antibiotics to fight antimicrobial resistance

C La Guidara, R Adamo, C Sala, F Micoli - International Journal of …, 2024 - mdpi.com
Antimicrobial resistance (AMR) is one of the most critical threats to global public health in the
21st century, causing a large number of deaths every year in both high-income and low-and …

[HTML][HTML] Biofilm Producing Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Humans: Clinical Implications and Management

A Kaushik, H Kest, M Sood, BW Steussy, C Thieman… - Pathogens, 2024 - mdpi.com
Since its initial description in the 1960s, methicillin-resistant Staphylococcus aureus (MRSA)
has developed multiple mechanisms for antimicrobial resistance and evading the immune …

Challenges in development of vaccines directed toward antimicrobial resistant bacterial species

M Brazzoli, D Piccioli, F Marchetti - Human Vaccines & …, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is considered by WHO one of the top ten public health
threats. New control strategies involving concerted actions of both public and private sectors …

[HTML][HTML] Toxin-neutralizing Abs are associated with improved T cell function following recovery from Staphylococcus aureus infection

M Kleinhenz, Z Li, U Chidella, W Picard, A Wolfe… - JCI insight, 2024 - ncbi.nlm.nih.gov
BACKGROUND T cell responses are impaired in Staphylococcus aureus–infected children,
highlighting a potential mechanism of immune evasion. This study tested the hypotheses …

[HTML][HTML] Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive …

O Sadones, E Kramarska, D Laverde, R Berisio… - BMC microbiology, 2024 - Springer
Abstract Background Enterococcus faecium and Staphylococcus aureus are the Gram-
positive pathogens of the ESKAPE group, known to represent a great threat to human health …

The effect of smoking on the increase of infectious diseases

K Ahmadi, Z Gharibi, P Davoodian, H Gouklani… - Tobacco and …, 2022 - thj.hums.ac.ir
Smoking is a well-known major risk factor for respiratory tract and other systemic infections.
The World Health Organization estimates that between 2000 and 2025, about 9% of deaths …