The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Transcription factor networks have evolved in order to control, coordinate, and separate, the
functions of distinct network modules spatially and temporally. In this review we focus on the …

Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Carbohydrate metabolism is essential for cellular energy balance as well as for the
biosynthesis of new cellular building blocks. As animal nutrient intake displays temporal …

Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …

Adipose tissue is a dynamic organ, well known for its function in energy storage and
mobilization according to nutrient availability and body needs, in charge of keeping the …

Metformin therapy lowers blood glucose in type 2 diabetes by targeting various pathways
including hepatic gluconeogenesis. Despite widespread clinical use of metformin the …

Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …

The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …